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Clinical Trials Directory

Enrolling Trials

Clinical Trial
Principal Investigator
IRB #
(Synovial Tissues) Rheumatoid Arthritis (RA) & Early Rheumatoid Arthritis (ERA) tissue study – Recruitment of patients undergoing synovectomy or upper extremity surgery (UES) or synovial biopsies.
Vivian P. Bykerk, BSc, MD, FRCPC
2014-317
A 5-Year Prospective Observational Registry to Assess Adverse Events of Interest and Effectiveness in Adults with Active, Autoantibody-Positive Systemic Lupus Erythematosus Treated with or without BENLYSTA™ (belimumab)
Doruk Erkan, MD, MPH
2015-090
A Pilot Study of a Dexamethasone Implant System in Humans
Mark P. Figgie, MD
2015-523
A Pilot Study to Evaluate the Safety and Efficacy of Amniotic Membrane Transplantation in Patients with Arthrofibrosis following Total Knee Arthroplasty
David J. Mayman, MD
2015-069
A Prospective Analysis of Connective Tissue Factors and Outcomes in Lumbar Spinal Fusion: A Pilot Study
Alexander P. Hughes, MD
2014-084
A Prospective Study of the Restoration Anatomic Dual Mobility (ADM) X3 Acetabular System
Geoffrey H. Westrich, MD
2015-100
A Randomized, Double-Blind Controlled, Multicenter Study in SLE Patients Given AKBM-3031or Placebo For 24 Weeks (Randomized Period) and Followed by an Open Label Extension (OLE) Treatment with AKBM-3031 for the Next 24 Weeks
Kyriakos A. Kirou, MD
2018-1099
A Study of Novel Immune Modulating Biomarkers in Patients with Spondyloarthritis with Axial Involvement
Vivian P. Bykerk, MD
2014-227
Abatacept (CTLA4-lg) for the Treatment of Relapsing, Non Severe, Granulomatosis with Polyangiitis (Wegener’s) (ABROGATE)
Robert F. Speira, MD
2015-267
Advanced MRI Applications for Mild Traumatic Brain Injury Phase 2
Teena Shetty, MD
2017-1390
An International, Open Label, Randomized Controlled Trial Comparing Rituximab with Azathioprine as Maintenance Therapy in Relapsing ANCA-Associated Vasculitis
Robert F. Spiera, MD
2014-284
APS ACTION (Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking) International Clinical Database and Repository.
Doruk Erkan, M.D
2014-252
Assessment of Frailty in Patients with Polymyalgia Rheumatica
Robert F. Spiera
2018-1823
Autoimmune Disease Registry and Repository
Jane E. Salmon, MD
2014-306
Barriers to Recovery in Post Concussive Syndrome
Teena Shetty, MD
2015-809
Bellumimab for the Treatment of Diffuse Cutaneous Systemic Sclerosis
Robert F. Spiera, MD
2014-279
Biomarkers in Spondyloarthropathies: A Case Control Study
Lisa A. Mandl MD, MPH
2014-240
Can Body Composition Help us Better Understand Outcomes in People with Lupus?
Lisa A. Mandl, MD, MPH
2017-1061
Consortium of Early Arthritis Cohorts USA (CATCH-US) – A prospective cohort study of adults with new onset inflammatory arthritis symptoms to understand predictors of optimal outcomes
Vivian P. Bykerk, MD
2014-229
Do Abnormal A-waves Predict IVIG Efficacy in Lower Motor Neuron Syndromes? A Double-Blind Crossover Design
Dale J. Lange, MD
2016-420
Does Chewing Gum Hasten Return of Bowel Function Post-operatively In Patients Following Spinal Surgery? A Prospective, Randomized Controlled  Trial
Russel C. Huang, MD
2014-065
Effect of Duloxetine on Opioid use after Total Knee Arthroplasty. A Double-blinded Randomized Control Trial
Jacques YaDeau, MD, PhD
2017-0655
Foot and Ankle Registry
Jonathan T. Deland, MD
2013-038
Fragile Bone Registry
Joseph M. Lane, MD
2015-165
Genetic Mapping Studies of Adolescent Idiopathic Scoliosis
Cathleen L. Raggio, MD
2014-375
Genetics InFormatics Trial (GIFT) of Warfarin to Prevent DVT
Anne R. Bass, MD
2014-225
Gleevec in the Treatment of Systemic Sclerosis - EXTENSION STUDY
Robert F. Spiera, MD
2014-280
Immune System Regulation in Autoimmune and Inflammatory Diseases
Mary K. Crow, MD
2014-221
Integrating PROMIS in SLE Clinical Care- Part 2
Lisa A. Mandl, MD, MPH
2018-2264
Intra-articular Autologous Bone Marrow Aspirate Injection for the Treatment of Knee Osteoarthritis: a Pilot Study with Radiological Follow-up
Gregory E. Lutz, MD
2016-0435
Longitudinal Evaluation of Hip Cartilage Degeneration: the effect of Femoroacetabular Impingement
Stephen Lyman, PhD
2016-168
Long-Term Outcomes of Hybrid Glenoid Compared With a Pegged Implant
Lawrence V. Gulotta, MD
2019-1818
Lower Limb Geometry in Individuals with Atypical Femoral Fractures
Joseph M. Lane, MD
2015-163
Motion and Muscle Analysis in Individuals with Femoroacetabular Impingement: A Pilot Study
Bryan T. Kelly, MD
2014-030
Mpfl Reconstruction for Recurrent Patellofemoral Instability: Rates of Failure vs. Radiographic Parameters
Beth E. Shubin Stein, MD
2013-112
Natural History and Outcome of Scleroderma Patients at High Risk or with Early Pulmonary Hypertension
Jessica Gordon, MD
2014-265
Nilotinib in the Treatment of Systemic Sclerosis
Robert F. Spiera, MD
2014-268
Pediatric and Adolescent Patellofemoral Instability
Beth Shubin Stein, MD
2014-087
Perioperative Flare in Rheumatoid Arthritis: Characterization of Clinical and Biologic Features
Susan M. Goodman, MD
2014-233
Phase II Trial of Abaloparatide vs. Placebo in Post-Menopausal Women Receiving Initial Spinal Fusion Surgery
Emily M. Stein, MD, MS
2018-0287
Predicting Clinical and Patient-Centered Outcomes after Surgery for Degenerative Spondylolisthesis
Carol A. Mancuso, MD
2015-237
PROMISSE: Predictors of Pregnancy Outcome: Biomarkers in Anti-Phospholipid Antibody Syndrome (APS) and Systemic Lupus Erythematosus (SLE)
Jane E. Salmon, MD
2014-309
Prospective Registry of Early Systemic Sclerosis (PRESS)- Phenotypic, Serologic, and Biomarker/Genetic Characteristics of Early Diffuse Cutaneous Scleroderma
Jessica K. Gordon, MD
2014-264
Prospective, Concurrently Controlled, Multi-Center Study to Evaluate the Safety and Effectiveness of the Spinal KineticsTM M6-C Artificial Cervical Disc Compared to Anterior Cervical Discectomy and Fusion (ACDF)  for the Treatment of Symptomatic Cervical Radiculopathy
Andrew A. Sama, MD
2014-104
Randomized Control Trial of Essential Amino Acid Supplementation in Protein Deficient Patients Following Total Knee Arthroplasty
David J. Mayman, MD
2015-067
Randomized Controlled Trial of Timing of Intravenous Tranexamic Acid in Total Knee Arthroplasty
Michael B. Cross, MD
2015-056
Scleroderma Cyclophosphamide or Transplantation (SCOT) Study
Robert F. Spiera, MD
26002
Scleroderma Registry and Repository (Old IRB #26069)
Robert F. Spiera, MD
2014-276
Studies of Immune Deregulation in Patients with Rheumatoid Arthritis, Polymyalgia Rheumatica and Vasculitis
Alessandra B. Pernis, MD
2014-312
Studies of Immune Deregulation in Patients with SLE
Alessandra Pernis, MD
2014-299
Synovial Pathology in Patients undergoing Hip Arthroscopy for Impingement and/or Labral Pathology: Role in Clinical Pre-Operative Symptoms and Post-Operative Outcomes
Bryan Kelly, MD
2014-198
The Center for Hip Preservation Outcomes Registry
Bryan T. Kelly, MD
2014-044
The Efficacy of Ultrasound Guided Glenohumeral Joint Injections of Platelet Rich Plasma (PRP) versus Hyaluronic Acid (HA) in the Treatment of Glenohumeral Osteoarthritis: A Randomized, Double-blind Control Trial (Old IRB #14134)
Jonathan S. Kirschner, MD, RMSK
2015-188
The Established Rheumatoid Arthritis Cohort
Susan M. Goodman, MD
2014-234
The Kathryn O. and Alan C. Greenberg Center for Skeletal Dysplasias Clinical Research Registry
Cathleen Raggio, MD
2014-166
The Myositis Registry and Repository - 2016
David Fernandez, MD
2014-263
The Natural History and Outcome of Scleroderma Patients at High Risk or with Early Pulmonary Hypertension: a Multicenter Study Performed by from the Scleroderma Clinical Trials Consortium (PHAROS)
Jessica K. Gordon, MD
2014-265
Undifferentiated Connective Tissue Disease (UCTD) and Overlap Registry
Lisa R. Sammaritano, MD
2014-311
VCRC Genetic Repository One Time DNA Protocol - 2013
Robert F. Spiera, MD
2014-278
VCRC Genetic Repository One Time DNA Protocol - 2016
Robert F. Spiera, MD
2014-278

Trials Not Enrolling

Clinical Trial
Principal Investigator
IRB #
Not enrolling new patients: A Study of Hyaluronan (Synvisc) for the Treatment of Osteoarthritis in the Thumb: Randomized Control Trial
Lisa A. Mandl, MD, MPH
26043
Not enrolling new patients: Arthroscopic Partial Meniscectomy in Osteoarthritis: A Randomized Control Trial
Lisa A. Mandl, MD, MPH
26035
Not enrolling new patients: Evaluation of Intra-articular Injuries as Predictors of Function and Arthritis
Robert G. Marx, MD
23108
Not enrolling new patients: Gleevec in the Treatment of Systemic Sclerosis
Robert F. Spiera, MD
27049
Not enrolling new patients: Pre-operative Identifiers Indicating Surgical Intervention for Wrist Deformity in Cerebral Palsy
Michelle G. Carlson, MD
26095
Not enrolling new patients: The Efficacy of Ultrasound-guided Percutaneous Needle Tenotomy (PNT) versus Platelet Rich Plasma (PRP) with PNT in the Treatment of Chronic Tendinosis
Jonathan S. Kirschner, MD
14135