Rheumatology

Rheumatology Research Highlights

Featured Highlight:

Photo of Lionel Ivashkiv, MD
Synergistic Activation of Inflammatory Cytokine Genes May Suggest New Therapeutic Approaches

Featuring Yu Qiao, PhD; Eugenia G. Giannopoulou, PhD; Chun Hin Chan; Sung-ho Park; Shiaoching Gong; Janice Chen; Xiaoyu Hu, MD, PhD; Olivier Elemento, PhD; Lionel B. Ivashkiv, MD

 
Photo of Alessandra Pernis, MD
Enhanced Rho-Associated Protein Kinase Activation in Patients with Systemic Lupus Erythematosus

Featuring Josephine Isgro, MD; Sanjay Gupta, PhD; Elzbieta Jacek, BA; Tanya Pavri, BA; Roland Duculan, MD; Mimi Kim, ScD; Kyriakos A. Kirou, MD, ScD; Jane E. Salmon, MD; Alessandra B. Pernis, MD

 
Photo of Lisa Mandl, MD
Increased Rates of Arthroplasty in Patients with SLE Seen Over a Fifteen-Year Period

Featuring Christina Mertelsmann-Voss, MD; Stephen Lyman, PhD; Ting Jung Pan, MPH; Susan Goodman, MD; Mark P. Figgie, MD; Lisa Mandl, MD MPH

 
Photo of Susan Goodman, MD
DMARD Therapy Associated with More Optimistic Expectations in RA Patients Undergoing TKA

Featuring Susan M. Goodman, MD; Lisa A. Mandl, MD, MPH; Mark P. Figgie, MD; Beverly K. Johnson, MD, MS; Michael Alexiades, MD; Hassan Ghomrawi, PhD, MPH

 
Photo of Michael D. Lockshin, MD
Managing Pregnant Patients with Antiphospholipid Antibody Syndrome: Risk Stratification May Help Refine Treatment Recommendations

Featuring Michael D. Lockshin, MD

 
Photo of Doruk Erkan, MD
Catastrophic Antiphospholipid Syndrome: Diagnosing a Rare but Highly Fatal Disease

Featuring Cassyanne L. Aguiar, MD; Doruk Erkan, MD

 
Photo of Nancy Pan
Surges in Anti-dsDNA Can Predict Severe Flares in SLE

Featuring Nancy Pan, MD; Isabelle Amigues, MD; Stephen Lyman, PhD; Roland Duculan, MD; Faisal Aziz, MD; Mary K. Crow, MD; Kyriakos A. Kirou, MD

 
Close up photo of a woman knitting
Synovial Fibroblasts Modulate Macrophage Function in Joint Inflammation

Featuring Laura T. Donlin, PhD; Arundathi Jayatilleke, MD; Eugenia G. Giannopoulou, PhD; George D. Kalliolias, MD, PhD; Lionel B. Ivashkiv, MD

 
Photo of Jessica Berman, MD
Doctors Using Excessive Medical Jargon Can Seem Unprofessional to Patients

Featuring Theodore R. Fields, MD; Anne R. Bass, MD; Juliet Aizer, MD, MPH; Stephen A. Paget, MD; Jessica Berman, MD

 
Photo of Carl P. Blobel, MD, PhD
ADAM17 Controls Cellular Signaling in Key Process of New Bone Growth

Featuring Katherine C. Hall; Daniel Hill; Miguel Otero, PhD; Darren A. Plumb, PhD; Dara Froemel, MD; Cecilia L. Dragomir, MD; Thorsten Maretzky, PhD; Adele Boskey, PhD; Licia Selleri, MD, PhD; Mary B. Goldring, PhD; Carl P. Blobel, MD, PhD

 
Photo of Carl P. Blobel, MD, PhD and Lionel B. Ivashkiv, MD
iRHOM2 is a Critical Pathogenic Mediator of Inflammatory Arthritis

Featuring Priya Darshinee A. Issuree, PhD; Thorsten Maretzky, PhD; Xiaoping Qing, MD, PhD; Steven L. Swendeman, PhD; Kyung-Hyun Park-Min, MD; Nikolaus Binder, PhD; George D. Kalliolias, MD, PhD; Anna Yarilina, PhD; Lionel B. Ivashkiv, MD; Jane E. Salmon, MD; Carl P. Blobel, MD, PhD

 
Photo of Thomas Lehman, MD
Male Children With Higher SLE Disease Activity in a US Cohort

Featuring Thomas J. A. Lehman, MD; Margaret Peterson, PhD; Alexa B. Adams, MD

 
Photo of Vivian P. Bykerk, MD
Timely, Effective Treatment of Rheumatoid Arthritis Reduces Disability Two Years Out

Featuring Vivian P. Bykerk, MD; Pooneh Akhavan, MD, FRCPC; Edward C. Keystone, MD, FRCPC; Juan Xiong, PhD; Bindee Kuriya, MD, FRCPC, MSc; Janet E Pope, MD, MPH, FRCPC; Gilles Boire, MD, MSc; Diane Tin, BPharm; Boulos Haraoui, MD, FRCPC; Carol A. Hitchon, MD

 
Photo of Alessandra Pernis, MD
Enhanced ROCK Activation in Lupus

Featuring Alessandra B. Pernis, MD; Josephine Isgro, MD; Sanjay Gupta, MD; Elzbieta Jacek; Tanya Pavri; Roland Duculan, MD; Kyriakos A. Kirou, MD; Jane E. Salmon, MD

 
 
Social Isolation Increases the Risk of Persistent Pain After Hip Replacement

Featuring Danielle Ramsden-Stein, MD; Susan M. Goodman, MD; Michael M. Alexiades, MD; Wei-Ti Huang, MS; Rebecca Zhu; Mark P. Figgie, MD; Lisa A. Mandl, MD, MPH

 
Photo of Jane Salmon, MD
Adverse Pregnancy Outcome in Lupus Pregnancies Associated with Angiogenic Factor Dysregulation

Featuring Jane E. Salmon, MD; Michael D. Lockshin, MD; Lisa R. Sammaritano, MD; Marta M. Guerra, MS

 
Photo of Robert F. Spiera, MD
Rituximab Shown Effective for Ear, Nose, and Throat Manifestations of GPA

Featuring Lindsay S. Lally, MD; Robert Lebovics, MD; Wei-Ti Huang, MS; Robert F. Spiera, MD

 
Photo of Susan Goodman, MD
First Large Outcomes Studies to Focus on Joint Replacements for Patients with Psoriatic Arthritis

Featuring Lisa A. Mandl, MD, MPH; Rebecca Zhul; Wei-Ti Huang, MS; Michael M. Alexiades, MD; Mark P. Figgie, MD; Susan M. Goodman, MD

 
Photo of Kyriakos Kirou, MD
High Type I Interferon in SLE Plasma Predicts Future Renal Disease

Featuring Mikhail Olferiev, MD; Elzbieta E. Jacek; Mari Lliguicota; Margaret Robotham; Wei-Ti Huang, MS; Elena Gkrouzman, MD; Mary K. Crow, MD; Kyriakos A. Kirou, MD, DSc

 
Photo of Steven R. Goldring, MD
New Discovery in Bone: The Protein Netrin1 is Required for Osteoclast Differentiation

Featuring P. Edward Purdue, PhD; Steven R. Goldring, MD

 
Photo of Jane Salmon, MD
Stimulating Cholinergic Neurotransmitter Receptors Modulates Inflammation in Lupus

Featuring Milena Vukelic, MD; Xiaoping Qing, MD, PhD; Patricia Redecha; Gloria Koo, PhD; Jane E. Salmon, MD

 
Photo of Ann Bass, MD
The Effect of Statin Therapy on the Risk of Blood Clots After Hip or Knee Arthroplasty

Featuring Yuo-Yu Lee; Stephen Lyman, PhD; Geoffrey H. Westrich, MD; Brian F. Gage, MD, MSc; Anne R. Bass, MD