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Research

Mentors and Training Opportunities

PostBac Researchers work under the mentorship of one or more of the HSS Research Faculty.

Training Opportunities

Current open PostBac Researcher projects:

"Mechanotransduction pathways in autoimmunity and musculoskeletal diseases"
Mentor: Dr. Alessandra Pernis
Proper regulation of mechanotransduction pathways is crucial for an effective response to an injury and to prevent pathological wound healing. Amongst these mechanosensitive pathways the ROCK kinases, ROCK1 and ROCK2, are critical coordinators of an injury response by promoting the recruitment of immune cells to sites of damage and by regulating the cross-talk of immune cells with tissue-resident cells. This project will evaluate the role of the ROCKs in immune cells and in mediating tissue damage in autoimmune and musculoskeletal diseases.

"ABC-mediated networks controlling autoimmunity and musculoskeletal diseases"
Mentor: Dr. Alessandra Pernis
Proper regulation of immune cell networks is crucial for an effective response to pathogens and to prevent autoimmune diseases. This project will evaluate the role of a novel B cell subset, ABCs (Age/Autoimmune associated B cells) in coordinating immune responses and in promoting the development of autoimmune and musculoskeletal diseases.

"Immune cell-mediated regulation of vascular-stromal compartment in lupus skin and lymph nodes" 
Mentor: Dr. Theresa Lu
The postbaccalaureate researcher's main focus will be to conduct research on the role of immune cells in regulating skin, lymph nodes, and the musculoskeletal system in the context of autoimmune diseases such as lupus, inflammatory arthritis, and scleroderma. 


To apply, complete the application form.

Program Committee

The Postbac Researcher Training Program is overseen by a committee of three faculty who provide program oversight and guidance: Dr. Ugur Ayturk, Assistant Scientist Bone Biology Program, Dr. Theresa Lu, Associate Scientist Autoimmunity and Inflammation Program and Dr. Christopher Mendias, Associate Scientist Orthopaedic Soft Tissue Research Program, along with participating Program faculty members and Program Director Dr. Risë Schwab. 

View a list of current PostBac Researchers.

 

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