The mission of the Arthritis and Tissue Degeneration Program is to define cellular and molecular mechanisms important in musculoskeletal tissue destruction and to develop novel approaches to preventing tissue destruction in patients with arthritis and related diseases.
The investigators of the Autoimmunity and Inflammation Research Program at Hospital for Special Surgery study the basic mechanisms of immune system function and the role of altered immune system activation, regulation, and effector function in the pathogenesis of the systemic autoimmune and inflammatory diseases.
The mission of the Department of Biomechanics is to apply principles of engineering and materials science to solve orthopedic problems by conducting basic and applied research that translates to the development of orthopedic devices and instrumentation aimed at improved patient care.
The Musculoskeletal Integrity Program's mission is to determine the biological, biochemical, and biomechanical mechanisms involved in musculoskeletal tissue development, degeneration, and repair, and to use that information to develop therapies to prevent or correct conditions in which these processes are impaired.
The Tissue Engineering, Regeneration and Repair Program's goal is to determine the biological, biochemical, bimolecular and biomechanical mechanisms responsible for development, damage, degeneration and healing of the musculoskeletal tissues, cartilage, meniscus, ligaments and tendons, and to use this information to develop new cell and tissue based strategies to prevent, repair, regenerate or replace the injured tissues.