> Skip repeated content

HSS Hosts 1st Research Day

Sponsored by the HSS Research Institute

HSS Research Day, Wednesday, May 3, 2023 features keynote speaker Henry Kronenberg, MD, Physician Investigator in the Endocrine Division at Mass General Research Institute and Professor of Medicine - Endocrinology at Harvard Medical School in Boston, MA.

Below is a schedule of events and agenda. All are welcome to attend!

Wednesday, May 3, 2023
8:30 am to 4:30 pm
Richard L. Menschel Education Center
Hospital for Special Surgery


Featured Speakers

Henry Kronenberg Headshot

Henry Kronenberg, MD

Professor of Medicine, Harvard Medical School 
Physician, Massachusetts General Hospital

Dr. Bostrom headshot

Mathias Bostrom, MD

Chief of ARJR service
Director, Arthroplasty Lab


Schedule of Events

8:00 am - 8:30 am

Welcome - Opening Remarks

Lionel Ivashkiv, MD
Chief Scientific Officer

8:35 am - 9:00 am

Mentorship Talk
(Moderators: Paoline Laurent, PhD and Genna Braverman, MD)
Mathias Bostrom, MD
Chief of ARJR Service, Director, Arthroplasty Lab
(Moderators: Paoline Laurent, PhD and Genna Braverman, MD)

9:00 am - 9:15 am

Thomas J. Kelly, MD, PhD and Sacha Lainovic, MBA
Co-Chairs, Research Committee of the Board of Trustees

9:15 am - 10:03 am

Morning Session 1
(Moderators: Theresa Lu, MD, PhD and Claire Eliasberg, MD)
Erikson Nichols, Pediatric Orthopedics 
(Mentor: E. R. Dodwell, MD, MPH Bone Health & Implant Integration) 
Monitoring with Tantalum Beads Demonstrates No Clinically Significant Growth Following Percutaneous Transphyseal Screw Epiphysiodesis
Kyle W. Morse, MD, Spine 
(Mentors: M. S. Iyer, MD & M. Greenblatt, MD/PhD, Bone Health & Implant Integration) 
A Stem Cell Basis for Spine Fusion
Carlos Aude, Rheumatology 
(Mentor: A. Bass, MD, Autoimmune Rheumatic Disease)     
Autoantibody Biomarkers of Immune-Related Adverse Events in Melanoma Patients Receiving Immune Checkpoint Inhibitor Therapy
Brian Oh, Research Institute 
(Mentor: K.H. Park-Min, PhD, Research, Autoimmune Rheumatic Disease/Bone Health & Implant Integration)
Glucocorticoid-induced osteoclastogenesis is compromised in glucocorticoid-induced osteonecrosis in SLE patients 

10:03 am - 10:15 am

Coffee Break

10:15 am - 10:30 am

Bryan Kelly, MD
President, Surgeon-in-Chief, and Medical Director

10:30 am - 11:30 am

Keynote Speaker
(Moderators: Lou Bridges, MD and Victoria Zyulina, PhD)
Dr. Henry Kronenberg, MD
Professor of Medicine, Harvard Medical School 
Physician, Massachusetts General Hospital
“The Remarkable Hypertrophic Chondrocyte”

11:30 am - 1:00 pm

Poster Session 1 (15-52) & Lunch

1:00 pm - 2:00 pm

Afternoon Session 1
(Moderators: Kyung-Hyun Park-Min, PhD and Stephanie Azzopardi)
Emma Billings, Research Institute 
(Mentor: E. Stein, MD, Bone Health & Implant Integration) 
Peripheral Cortical Bone Density Predicts Vertebral Bone Mineral Properties in Spine Fusion Surgery Patients
Ruoxi Yuan, Ph.D., Research Institute 
(Mentor: L. Ivashkiv, MD, Inflammation & Arthritis)
SREBP Transcription Factors Regulate Myeloid Cell Function and Inflammatory Responses 
William Chan, Anesthesiology
(Mentor: A. Sideris, MD, Musculoskeletal Pain)
 A survey study assessing prescribers’ opioid tapering instructions to patients after orthopedic surgery
Erin Berube, Biomechanics 
(Mentor: C. Imhauser, PhD, Joint Preservation and Regeneration)
Biomechanical Analysis of Posterior Stabilized Total Knee Arthroplasty Reveals Sagittal Plane Laxity in Midflexion to be Highly Sensitive to Coronal Laxity in Extension and MCL Pretension
Yongli Qin, Ph.D., Research Institute 
(Mentor: B. Zhao, PhD, Bone Health & Implant Integration)
Identification of AdipoQ+ bone marrow cells as the major cellular source of M-CSF that dominates bone marrow macrophage development, osteoclastogenesis and bone mass 

2:00 pm - 2:15 pm

Coffee Break

2:15 pm - 3:15 pm

Afternoon Session 2
(Moderators: Baohong Zhao, PhD and Bikash Mishra)
Sara Sacher, MS, Radiology/MRI Lab
(Mentors: Hollis Potter, MD, Matthew Koff, PhD,  Bone Health & Implant Integration)
Flexural Rigidity of THAs is Associated with MRI and Histological findings
Ian Mantel, Research Institute 
(Mentor: L. Donlin, PhD, Research, Inflammation & Arthritis)
Pro-fibrotic SPP1hi macrophages are polarized by stromal and endothelial-derived soluble factors in myeloid cell-rich rheumatoid arthritis synovium
Joaquin Palma, MD, Foot & Ankle service 
(Mentor: C. Demetracopoulos, MD, Inflammation & Arthritis)
Influence of Double Hindfoot Arthrodesis and the Sequence of Joint Fusion on Ankle Kinematics: A Cadaveric Gait Simulation Study
Jacob Moore, Research Institute 
(Mentor: U. Ayturk, PhD, Research, Bone Health & Implant Integration)
Clec3b+ Cells Contribute to Fracture Healing and Heterotopic Ossification
Claire Marie Kemp, Research Institute
(Mentor: C. Dahia, PhD, Research, Musculoskeletal Pain)
Molecular insights into intervertebral disc pathogenesis provide clues for back pain and discomfort in patients

3:15 pm - 4:30 pm

Poster Session 2 (53-89)

4:30 pm - 6:30 pm

Closing Remarks, Award Ceremony, Cocktail Hour