Buerger's disease (thrombangiitis obliterans) is a disorder where arteries and veins of the limbs (legs, arms, or both) become inflamed and clotted. This causes too little blood to flow to the limbs. The lack of blood circulation can lead to gangrene (tissue death), and the affected arm or leg may need to be amputated (surgically removed).
Buerger’s disease is not common and is difficult to diagnose. Symptoms include severe pain in the lower arms or legs, particularly in hands and feet. Open sores may also appear in these parts of the body.