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Shari Jawetz, MD

Emily Margaret Stein, MD, MS


Internal Medicine, Endocrinology, Metabolic Bone
Shari Jawetz, MD

Emily Margaret Stein, MD, MS


Hospital for Special Surgery
519 East 72nd St, Suite 202
New York, NY 10021

Tel: 212.606.1970
Fax: 212.606.1967

Hospital for Special Surgery
519 East 72nd St, Suite 202
New York, NY 10021

Tel: 212.606.1970
Fax: 212.606.1967

Dr. Emily Stein is an Associate Research Scientist and Associate Attending Physician at The Hospital for Special Surgery. She received her undergraduate degree from Yale University, where she was elected to Phi Beta Kappa and graduated Magna Cum Laude. She received her medical degree from the Albert Einstein College of Medicine where she received a Rudin Fellowship for academic excellence and was elected to Alpha Omega Alpha. She completed her internship and residency at Columbia Presbyterian Medical Center. She was a fellow in Endocrinology and Metabolism at the combined program at New York Hospital/Weill Cornell Medical Center and Memorial Sloan Kettering Cancer Center. She also completed a Masters Degree in Clinical Investigation at the Cornell Graduate School.

Dr. Stein is a member of the American Society of Bone and Mineral Research, and received both a Young investigator Award and Junior Faculty Osteoporosis Research Award from this society. Her research, supported by the National Institutes of Health, American Society of Bone and Mineral Research, as well as private foundations has focused on investigating the quality of bone in patients with osteoporotic fractures, and the skeletal effects of glucocorticoids, chronic kidney disease, or and transplant and bariatric surgery. She has also studied abnormalities of vitamin D metabolism in different populations.

Her clinical practice is focused on patients with osteoporosis and metabolic bone disease. Dr. Stein has also played a role in shaping evidence based clinical practice decisions in the field, serving as a member of the American Society of Bone and Mineral Research Professional Practice Committee, the International Society of Clinical Densitometry Scientific Advisory Council and the American College of Rheumatology Glucocorticoid Induced Osteoporosis Quality Measure Development Panel.

Back in the Game Patient Stories

Appointments

Associate Attending Physician, Hospital for Special Surgery
Associate Research Scientist, Hospital for Special Surgery

Specialty

Internal Medicine, Endocrinology, Metabolic Bone

Special Expertise

Osteoporosis, Metabolic Bone Disorders, Calcium and Phosphate Disorders

Awards

American Society for Bone and Mineral Research Young Investigator Travel Award, 2012
Junior Faculty Osteoporosis Research Award, American Society for Bone and Mineral Research, 2011
American Society for Bone and Mineral Research Young Investigator Travel Award, 2011
American Society for Bone and Mineral Research Young Investigator Award, 2010
Endocrine Society Travel Award, 2009
Clinical Research Feasibility Funds (CreFF) Award, Awarded by the Weill Cornell CTSA, 2005
Alpha Omega Alpha 2001 Rudin Distinguished Scholar, 1997-2001
American Medical Women's Association Janet M. Glasgow Achievement Citation, 2001
College Council Award Yale University, 1997

Affiliations

NIH Skeletal Biology Development and Disease Study Section (2016 Temporary Member)
American Society for Bone and Mineral Research, Development Committee (term 2015-2018)
American Society for Bone and Mineral Research, Professional Practice Committee (term 2012-2015)
International Society for Clinical Densitometry, Scientific Advisory Council (term 2012-2015) American College of Rheumatology – Glucocorticoid Induced Osteoporosis Quality Measure Development Panel, member, 2011

Languages

English

Education

Albert Einstein College of Medicine, New York

Internship

Internal Medicine, New York Presbyterian Hospital - Columbia

Residency

Internal Medicine, New York Presbyterian Hospital - Columbia

Fellowship

Endocrinology and Metabolism, Weill Cornell Medical College/ Memorial Sloan Kettering Cancer Center

Certification

08/2004 American Board of Internal Medicine
10/2006 American Board of Internal Medicine, Endocrinology and Metabolism

State Licensure

New York

Patient Education by Dr. Stein on HSS.edu

Selected Books/Chapters

Stein, E., Shane, E. Secondary osteoporosis. In: Bilezikian, J. editor Endocrinology and Metabolism Clinics of North America. Philadelphia: W.B. Saunders Company; 2003. 114-134.

Stein, E., Shane, E. Bone loss in patients before and after lung transplantation. In: Compston, J. and Shane, E. editors. Bone Disease of Organ Transplantation. Amsterdam: Elsevier Academic Press; 2005. 303-318.

Stein, E., Ebeling, P., Shane E. Post-transplant Osteoporosis. In: Breen, T. editor. Endocrinology and Metabolism Clinics of North America. 2007. 36(4): 937-63.

Stein, E, Shane, E. Transplantation Osteoporosis. In: Adler, R. editor. Osteoporosis, Pathophysiology and Clinical Management. New York: Humana Press; 2010. 569-620.

Stein, EM, Compston, J, Shane, E. Transplantation Osteoporosis. In: Bilezikian, JP. Editor. Osteoporosis in Men. London: Elsevier; 2010. 443-452.

Yin M, Stein E. The effect of antiretrovirals on vitamin D. Clin Infect Dis. 2011 Feb 1;52(3):406-8.

Stein EM, Shane E. Vitamin D in organ transplantation. Osteoporos Int. 2011 Jul;22(7):2107-18. Epub 2011 Jan 5. Epub 2011 Jan 5.

Stein EM, Shane E. Osteoporosis in Organ Transplant Patients. In: Marcus R, Feldman D, Dempster D, Luckey M, Cauley J Editors. Osteoporosis 4th Edition. San Diego: Elsevier: 2013. 1349-1374.

Stein EM and Silverberg SJ. Bone loss after bariatric surgery: causes, consequences and management. Lancet Diabetes Endocrinol 2014; 2: 165-174.doi:10.1016/S0140-6736(08)61345-8.

Sutter SA and Stein EM. The Skeletal Effects of Inhaled Glucocorticoids. Curr Osteoporos Rep. 2016 Jun;14(3):106-13. doi: 10.1007/s11914-016-0308-1.

Selected Publications

Stein EM, Liu XS, Nickolas TL, Cohen A, Thomas V, McMahon DJ, Zhang C, Yin PT, Cosman F, Nieves J, Guo XE, Shane E. Abnormal microarchitecture and reduced stiffness at the radius and tibia in postmenopausal women with fractures. J Bone Miner Res. 2010 Dec;25(12):2572-81.

Stein EM, Liu XS, Nickolas TL, Cohen A, Thomas V, McMahon DJ, Zhang C, Cosman F, Nieves J, Greisberg J, Guo XE, Shane E. Abnormal Microarchitecture and Stiffness in Postmenopausal Women with Ankle Fractures. J Clin Endocrinol Metab. 2011 Jul;96(7):2041-8.

Stein EM, Ortiz D, Jin Z, McMahon DJ, Shane E. Prevention of fractures after solid organ transplantation: a meta-analysis. J Clin Endocrinol Metab. 2011 Nov;96(11):3457-65.

Stein EM, Liu XS, Nickolas TL, Cohen, A, McMahon DJ, Zhou B, Zhang C, Kamanda-Kosseh M, Cosman F, Nieves J, Guo XE, Shane E. Microarchitectural Abnormalities are More Severe in Postmenopausal Women with Vertebral Compared to Non-vertebral Fractures. J Clin Endocrinol Metab. 2012 Oct;97(10):E1918-26. doi: 10.1210/jc.2012-1968.

Stein EM, Silva BC, Boutroy S, Zhou B, Wang J, Udesky J, Zhang C, McMahon DJ, Romano M, Dworakowski E, Costa AG, Cusano N, Irani D, Cremers S, Shane E, Guo XE, Bilezikian JP. Primary hyperparathyroidism is associated with abnormal cortical and trabecular microstructure and reduced bone stiffness in postmenopausal women. J Bone Miner Res. 2013 May;28(5):1029-40.

Stein EM, Carrelli A, Young P, Bucovsky M, Zhang C, Schrope B, Bessler M, Zhou B, Wang J, Guo XE, McMahon DJ, Silverberg SJ. Bariatric Surgery Results in Cortical Bone Loss. J Clin Endorinol Metab. 2013 Feb; 98(2):541-9.

Stein EM, Kepley A, Walker MD, Nickolas TL, Nishiyama KK, Zhou B, Liu XS, McMahon DJ, Zhang C, Boutroy S, Cosman F, Nieves J, Guo, XE, Shane E. Skeletal Structure in Postmenopausal Women with Osteopenia and Fractures is Characterized by Abnormal Trabecular Plates and Cortical Thinning. J Bone Miner Res. 2014;21(5): 1101-1109.

Sutter S, Nishiyama K, Kepley A, McMahon DJ, Zhou B, Guo X, Stein EM. Abnormal Microarchitecture and Stiffness in Postmenopausal Women Treated with Glucocorticoids. J Clin Endocrinol Metab. 2014 Nov; 99(11): 4231-40.

Stein EM, Rogers H, Leib A, Young P, McMahon DJ, Nishiyama KK, Guo XE, Lewis S, Green P, Shane E. Abnormal Skeletal Strength and Microarchitecture in Women with Celiac Disease. J Clin Endocrinol Metab 2015 Jun;100(6):2347-53. doi: 10.1210/jc.2015-1392. Epub 2015 Apr 13.

Carrelli A, Bucovsky M, Horst R, Cremers S, Zhang C, Bessler M, Schrope B, Evanko J, Blanco J, Silverberg SJ, Stein EM. Vitamin D Storage in Adipose Tissue of Obese and Normal Weight Women. J Bone Miner Res. 2016 Aug 20. doi: 10.1002/jbmr.2979. [Epub ahead of print]

 

For more publications, please see the PubMed listing.

Research Interests

Dr. Stein is a clinical researcher in the field of metabolic bone disease. She has extensive research experience in the areas of postmenopausal osteoporosis, glucocorticoid induced osteoporosis, vitamin D metabolism, and the use of non-invasive techniques to evaluate bone structure and strength, aspects of bone quality.

Dr. Stein has been Principal Investigator (PI) or Co-investigator of studies investigating the pathophysiology and treatment of postmenopausal and secondary osteoporosis. Her research has involved several multi-disciplinary collaborations, with orthopedists, rheumatologists, nephrologists, and engineers. I received a K23 award from the NIH to evaluate the effects of parathyroid hormone and chronic kidney disease on skeletal microarchitecture and strength in postmenopausal women. This work has led to the identification of several novel microstructural mechanisms for fragility fractures. Recent work has focused on addressing the mechanisms by which various disease states and medications negatively impact bone quality. She was the recipient of a Junior Faculty Osteoporosis Research Award from the ASBMR to investigate the effects of oral glucocorticoids on skeletal structure and strength and is currently Principal Investigator of a study investigating the skeletal impact of inhaled glucocorticoids.

Dr. Stein has also served as PI or Co-investigator for randomized clinical trials aimed at improving skeletal outcomes with different pharmacologic and behavioral interventions, including teriparatide treatment for premenopausal women with idiopathic osteoporosis, bisphosphonate treatment for prevention of bone loss after solid organ transplantation, treatment of vitamin D deficiency in obese individuals prior to bariatric surgery, and potassium citrate treatment for prevention of postmenopausal bone loss. She has served as a member of the Data Safety Monitoring Board for two randomized clinical trials.

Other research interests include investigation of bone quality deficits in other disease states as well as the relationship between pre-operative bone quality and outcomes after orthopedic procedures, and the creation of clinical trials investigating whether different pharmacologic therapies can improve these outcomes.