Paget's Disease

A chronic bone disorder, Paget's disease, or osteitis deformans, generally affects new bone growth in adults and leads to the formation of abnormally large, weak bone that breaks easily. The malformed bone can lead to serious conditions such as joint, spine, and limb deformities, as well as pinched nerves and enlarged skull.

It is unknown what causes Paget's disease and there is no cure. Treatment includes imaging (x-ray), blood, and bone testing; medications to slow bone growth and manage pain; and surgery to repair and control the abnormal bone growth.


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