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Dr. Edward DiCarlo, Pathologist

Yaxia Zhang, MD, PhD


Pathology
Dr. Edward DiCarlo, Pathologist

Yaxia Zhang, MD, PhD


Hospital for Special Surgery
535 East 70th Street
New York, NY 10021

Tel: 212.606.1259
Fax: 212.606.1910
Hospital for Special Surgery
535 East 70th Street
New York, NY 10021

Tel: 212.606.1259
Fax: 212.606.1910

Dr. Yaxia Zhang is the Chief Clinical Pathologist in the HSS Department of Pathology and Laboratory Medicine. Dr. Zhang comes to HSS from Cleveland Clinic, where she practiced in the Department of Pathology as orthopedic pathologist, molecular cytopathologist from 2013-2017.

Dr. Zhang specializes in non-neoplastic and neoplastic orthopedic pathology, and molecular cytopathology, especially investigating the molecular mechanisms of orthopedic diseases. She is also interested in success and failure of reconstructive orthopedic procedures, devices and bone graft substitute materials.

Back in the Game Patient Stories

Appointments

Chief Clinical Pathologist, Hospital for Special Surgery
Attending Pathologist, Hospital for Special Surgery

Specialty

Special Expertise

Non-neoplastic and neoplastic orthopedic pathology
Reconstructive orthopedic procedures, devices and bone graft substitute materials

Procedures

Interpretation of bone, joint, soft tissue and general surgical pathology specimens
Evaluation of retrieved orthopedic devices
All laboratory medicine (excluding blood banking)

Awards

Mentor for the 1st, 2nd resident abstract competition awards at the Cleveland Society of Pathology (CSP), 2016
Award on Musculoskeletal (Bone Intervention), Radiological Society of North America (RSNA) (Co-author), 2016
Outstanding Original Investigation by American Association for Bronchology and Interventional Pulmonology (Co-author), 2016
3th Annual Zubrod Clinical/Translational Research Award, Sylvester Comprehensive Cancer Center, University of Miami, 2012

Affiliations

Orthopedic Research Society
International Skeletal Society
College of American Pathologists
United States and Canadian Academy of Pathology
American Society of Cytopathology

Insurance Information

Aetna
Blue Cross Blue Shield PPO HMO POS
Blue Cross Blue Shield Pathway
Blue Cross Blue Shield Pathway Enhanced
Cigna
Connecticare
Emblem Selectcare
HIP
Medicare
Oxford
Oxford Medicare
United Healthcare
United Healthcare Compass

Please do not hesitate to contact our office if you have questions regarding your insurance coverage. You may still have coverage subject to the availability of 'out-of-network' benefits.

Education

Zhejiang University, School of Medicine, 1997
University of Miami, Miller School of Medicine, 2005

Residency

University of Miami, Jackson Memorial Hospital, 2011

Fellowship

University of Miami, Jackson Memorial Hospital, 2013

Certification

Anatomic and Clinical Pathology, 2011
Cytopathology, 2012
Molecular Genetic Pathology/Orthopedic Pathology, 2013

State Licensure

New York, Florida, Ohio

Selected Books/Chapters

Bauer TW, Zhang Y. Implants and Implant Reactions. Diagnostic pathology. 2016, 22(10):384-396.

Zhang Y, Rosenberg AE. Cartilaginous tumors of soft tissue and joints. Diagnostic pathology. 2014, 20 (5):200-207

Zhang Y, Rosenberg AE. Bone-Forming Tumors. Surg Pathol Clin 2017;10:513-535, doi: 10.1016/j.path.2017.04.006.

Zhang Y, Rosenberg AE, Layfield LJ, Nielson GP. Chapter 14. Neoplastic and Tumor-like lesions of bone. Chapter in Silberberg's Principles and Practice of Surgical Pathology and Cytopathology. Cambridge University Press, 5th edition, 2014.

Zhang Y, Nosé V. V. McCune-Albright syndrome. Chapter in Diagnostic Pathology. Endocrine. Amirsys, 2012.

Zhang Y. Chapter 12-Molecular markers of soft tissue and bone tumors. Molecular Cytopathology. Springer Switzerland, 2016.

Zhang Y, Qian X. Chapter 12- Soft tissue tumor. Atlas of non-GYN cytopathology. Springer. 2017

Zhang Y and Rosenberg AE. Chondrogenetic tumor. Pediatric Bone and Joint Pathology. Cambridge University Press. In Press 2017

Marilyn M. Bui, Yaxia Zhang, and Evita Henderson-Jackson. Resection Specimen Handling, Staging, and Reporting Bone Tumor Specimens. Grossing Manual and Resection Pathology: Specimen Handling, Staging Pitfalls, and Standard Reporting. CAP Press. In Press 2018

Zhang Y, Rosenberg AE. The pathology of bone sarcoma. Sarcoma Oncology: A Multidisciplinary Approach. In press.

Selected Publications

Zhang Y, Mejia AP, Temple HT, Trent J, Rosenberg AE. Squamous cell carcinoma arising in dedifferentiated chondrosarcoma proved by isocitrate dehydrogenase mutation analysis. Human Pathology. 2014, Jul;45 (7):1541-5

George J, Zhang Y, Jawad M, Faour M, Klika AK, Bauer TW, Higuera CA. Diagnostic Utility of Histological Analysis for Detecting Ongoing Infection During Two-Stage Revision Arthroplasty in Patients With Inflammatory Arthritis. J Arthroplasty. 2017 Dec 29 (Epub ahead of print).

Zhang Y, Mejia AP, Temple HT, Trent J, Rosenberg AE. Squamous cell carcinoma arising in dedifferentiated chondrosarcoma proved by isocitrate dehydrogenase mutation analysis. Human Pathology. 2014, Jul;45 (7):1541-5

Zhang Y, Ilaslan H, Hussain MS, Bain M, BauerTW. Solitary C1 Spinal Osteochondroma causing vertebral artery compression and acute cerebellar infarct. Skeletal Radiology. 2015, Feb; 44(2):299-302.

Inyang A, Mertens F, Puls F, Vaiyapuri S, Inwards C, Folpe A, Lee CH, Yoshida A, Zhang Y, Symmans P, Rubin B, Nielsen GP, Rosenberg AE. Primary Pseudomyogenic hemangioendothelioma of Bone. Am J Surg Pathol. 2016, May; 40(5):587-98.

Zhang Y, Ilaslan H, Krishnaney AA, Bauer TW. Morphologic transformation of giant cell tumor of bone after treatment with denosumab. JBJS Case Connect 2016:6e74, http://dx.doi.org/10.2106/JBJS.CC.16.00015.

Kwiecien G, George J, Klika AK, Zhang Y, Bauer TW, Rueda CA. Intraoperative Frozen Section Histology: Matched for Musculoskeletal Infection Society Criteria. J Arthroplasty. 2017 Jan;32(1):223-227.

Zhang Y, Joyce M, Schils J, Bauer TW. Coexisting sarcoidal granulomatous inflammation and diffuse tenosynovial giant cell tumor of the knee after a total knee replacement: a case report. Skeletal Radiol. 2016 Dec;45(12):1735-1740.

Zhang Y, Ilaslan H, Bauer TW. Giant cell tumor of bone: imaging and histology changes after denosumab treatment: Comment on: von Borstel D, Taguibao RA, Strle NA, Burns JE. Giant cell tumor of the bone: Aggressive case initially treated with denosumab and intralesional surgery. Skeletal Radiol 2017;46:571-578.

Ilaslan H, Schils J, Joyce M, Shah C, Zhang Y. Radiation-induced focal cortical necrosis of the femur presenting as a lytic lesion. Skeletal Radiol 2017; doi: 10.1007/s00256-017-2715-5.

Selected Presentations

Buethe JY, Lance C, Kosmas C, Gholamrezanezhad A, Abdul-Karim F, Zhang Y, Robin MR. Short and Long Term Effects of In Vivo Periarticular Osseous Ablation on Porcine Articular Cartilage: Comparison between Cryoablation and Radiofrequency Ablation. Platform presentation. Radiological Society of North America Annual meeting. Chicago.2016

Lu H, Brainard J, Allende D, Liu X, and Zhang Y. Lymphoid Enhancer Binding Factor 1 (LEF1) and Paired Box Gene 8 (PAX8): A Limited Immunocytochemistry Panel to Distinguish Solid Pseudopapillary Neoplasms and Pancreatic Neuroendocrine Tumors on Endoscopic Ultrasound-Guided Fine-Needle Aspirates. STOWELL-ORBISON/SURGICAL PATHOLOGY/AUTOPSY AWARD POSTER SESSION 106th USCAP Annual meeting. San Antonio. 2017

Lu, H, Elsheikh T, and Zhang Y. Polyoma (BK) Virus Cytopathic Effect in Urine Cytology Is Not Associated with High Risk of Developing Urothelial Carcinoma. Platform Presentation. 106th USCAP Annual meeting. San Antonio. 2017

Kilpatrick SE, Zhang Y, Sundaram. Disseminated Langerhans Cell Histiocytosis. International Skeletal Society Annual Meeting, 08/27-08/31, New York, NY, 2017

Kuyumcu, G, Ilaslan H, Zhang Y. Winalski C. Laryngeal and Tracheal chondrosarcomas, a single center experience. Oral presentation. AARS Annual Meeting. New Orleans. 2017

Zhang Y, Winalski C, Ilaslan H. Dedifferentiated Chordoma. International Skeletal Society Annual Meeting, 08/27-08/31, New York, NY, 2017

Inyang A, Mertens F, Puls F, Vaiyapuri S, Inwards C, Folpe A, Lee CH, Yoshida A, Zhang Y, Symmans P, Rubin B, Nielsen GP, Rosenberg AE. Primary Pseudomyogenic Hemangioendothelioma of Bone. Platform 104th USCAP Annual meeting in Boston.

Zhao L, Doxtader E, Lin X, and Zhang Y. Reliable Detection of EGFR Mutation by Allele-Specific PCR and ALK Gene Rearrangement by FISH in Non-Small Cell Lung Carcinoma Using Liquid-Based Cytology Sample: High Concordance with Next-Generation Sequencing Performed on Cell Block Material. Poster Presentation ASC 65th Annual Scientific Meeting. Phoenix. November 10-13, 2017

Lin X, Laskin WB, and Zhang Y. Utility of MDM2, p16, HMB-45 and Melan A Immunohistochemistry in Differentiating Angiomyolipoma from Well-Differentiated Liposarcoma. Poster Presentation ASC 65th Annual Scientific Meeting. Phoenix. November 10-13, 2017.

George J, Zhang Y, Jawad M, Faour M, Klika AK, Barsoum WK, Bauer TW, Higuera CA. Utility of histological analysis for diagnosis of persistent infection during two-stage revision arthroplasty in patients with inflammatory arthritis. Poster at the AAHKS meeting, Dallas, TX 11/03/2017.

Research Interests

Dr. Zhang's main research focus has been to investigate molecular mechanisms of primary bone neoplastic and non-neoplastic diseases. She collaborates with surgeons, radiologists, and biomedical engineers to correlate clinical, intraoperative observations with the microscopic appearance of patients' tissues. She also studies the optimum use of laboratory tests for the care of orthopedic patients.