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Michael J. Klein, MD



Dr. Michael J. Klein is an Attending Pathologist at Hospital for Special Surgery. He specializes in the diagnosis and treatment of bone and soft tissue tumors, non-neoplastic bone diseases, joint diseases, and laboratory medicine specific to bone and soft tissue disease.

Dr. Klein received his medical degree from Temple University in Philadelphia, PA, and then completed his internship, residency, and fellowship at New York University Medical Center. Throughout his career, he has been an active member in several professional organizations, has maintained numerous editorial appointments, and has published extensively.

In addition, Dr. Klein has been awarded a number of prestigious honors. These include New York University Medical Center's Twenty-Five Year Service Award and the International Skeletal Society's Corrine Farrell Award. He has consistently been ranked as one of the Best Doctors in America and has been recognized often for his excellence in teaching.


Special Expertise

Diagnosis and treatment of bone and soft tissue tumors
Diagnosis and treatment of non-neoplastic bone diseases
Diagnosis and treatment of joint diseases
Laboratory medicine specific to bone and soft tissue diseases


Interpretation of bone, joint, soft tissue, and general surgical pathology
All laboratory medicine (excluding blood banking)

Patient Stories


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Attending Pathologist, Hospital for Special Surgery


International Skeletal Society
American Society of Clinical Pathologists
United States and Canadian Academy of Pathology
College of American Pathologists


Anatomical /Clinical Pathology, American Board of Pathology, 1978
Voluntary Recertification, American Board of Pathology, 2004


Leonard Robinson Award for Excellence in Resident Education, 2008
Best Doctors in America, 2003-2008
Founders Lecturer, International Skeletal Society, 2005
Henry L. Jaffe Lecturer, Hospital for Joint Diseases Orthopaedic Institute, 2003
Twenty-Five Year Service Award, NYU School of Medicine, 2000
Corrine Farrell Award, International Skeletal Society, 1996
Excellence in Teaching Awards, Mt. Sinai School of Medicine, 1989-1991, 1993-1995, 1998, 2003


MD, Temple University, Philadelphia, PA, 1973


New York University Medical Center, New York, 1974


New York University Medical Center, New York, 1977


New York University Medical Center, New York, 1979

State Licensure



Publications by

Editorial Appointments

Editorial Board, Human Pathology
Editorial Board, Skeletal Radiology
Editorial Board, Advances in Anatomical Pathology
Editorial Board, (Consultant Editor of Research) The Journal of Bone and Joint Surgery (American)

Selected Journal Articles

Hermann, G, Abdelwahab, IF, and Klein, MJ: Musculoskeletal Involvement by Malignant Lymphoma. In Radiological Imaging in Hematological Malignancies, Guermazi, A, ed. (Heidelberg:Springer-Verlag), 159-174, 2004.

Klein, MJ: Bones (In The Cancer Handbook, 2nd Edition. Alison, MR, ed. John Wiley and Sons, Ltd. Chichester, West Sussex, UK, 2007), Chapter 54:733-748.

Klemm, KM, Klein, MJ: Biochemical Markers of Bone Metabolism. In Pincus et.al., Davidson and Henry’s Clinical Diagnosis and Management by Laboratory Methods. 21st ed. (Philadelphia:Saunders-Elsevier) 170-184. 2007.

Klein, MJ: Bone Tumors. In Schwab, M. Encyclopedia of Cancer, 2nd Edition. (Heidelberg:Springer-Verlag) - (in press).

Hoch, BL, Klein, MJ, and Schiller, AL: Bones and Joints. In Rubin’s Pathology: Clinicopathologic Foundations of Medicine, 5th Edition. Rubin, R, Strayer, DS, eds. (Philadelphia, Wolters Kluwer/Lippincott Williams and Wilkins), 2007.

Hameed, O, Klein, MJ: Bone Neoplasms and other Non-Metabolic Disorders. In The Washington Manual of Surgical Pathology, Humphrey, PA, Dehner, LP, Pfeifer, JD, eds.(Philadelphia, Wolters Kluwer/Lippincott, Williams and Wilkins) 630-652, 2008.

Klein, MJ: Ewing’s Sarcoma and Primitive Neuroectodermal Tumor. In Bone and Soft Tissue Pathology: Foundations in Diagnostic Pathology. Folpe, AL, Inwards, CY, eds. (Philadelphia: Elsevier) - (in press).

For more publications, please see the PubMed listing.


Research Interests

Pathoradiographic correlation methods
Use of informatics to improve diagnoses and clinical research methods

Industry Relationships

Industry Relationships

One of the goals of HSS is to advance the science of orthopedic surgery, rheumatology, and related disciplines for the benefit of patients. Physicians at HSS may collaborate with outside companies for education, research and medical advances. HSS supports this collaboration in order to foster medical breakthroughs; however HSS also believes that these collaborations must be disclosed.

As part of the disclosure process, this website lists physician collaborations with outside companies. The disclosures are provided by information provided by the physician and other sources and are updated regularly. Further information may be available on individual company websites.

Below are the healthcare industry relationships reported by Dr. Klein as of December 03, 2019.

  • American Registry of Pathology - Book Royalties
  • Bristol Myers Squibb - Ownership interest
  • Eli Lilly & Company - Ownership interest
  • Johnson & Johnson, Inc. - Ownership interest
  • Pfizer, Inc. - Ownership interest
  • United Health Group - Ownership interest

By disclosing the collaborations of HSS physicians with industry on this website, HSS and its physicians make this information available to their patients and the public, thus creating a transparent environment for those who are interested in this information. Further, the HSS Conflicts of Interest Policy does not permit physicians to collect royalties on products developed by him/her that are used on patients at HSS.

Patients should feel free to ask their HSS physicians questions about these relationships.