Senior Scientist and Director, Laboratory for Soft Tissue Research, Research Division, Hospital for Special Surgery
Professor of Applied Biomechanics in Orthopaedic Surgery, Department of Orthopaedics, Weill Medical College of Cornell University
Associate Professor, Graduate Faculty, Physiology, Biophysics, and System Biology Program, Weill Medical College of Cornell University
Grant Professor of Biomedical Engineering, Department of Mechanical Engineering, and Co-Director, Center for Biomedical Engineering, City College School of Engineering
Adjunct Professor, The Graduate School and University Center’s Ph.D. Program in Engineering, City College School of Engineering
Adjunct Full Professor, Department of Physics and Engineering Physics, Fordham University
Lucchinetti, E., Adams, C.S., Horton Jr., W.E. and Torzilli, P.A.(2002) Cartilage Viability After Repetitive Loading. A Preliminary Report. Osteoarthritis & Cartilage, 10:71-81.
Chen, C-T, Bhargava, M.., Lin, P. and Torzilli, P.A.. (2003) Time, Stress, and Location Dependent Chondrocyte Death and Collagen Damage in Cyclically Loaded Articular Cartilage. Journal of Orthopaedic Research, 21:888B898.
Milentijevic, D., Helfet, D.L .and Torzilli, P.A. (2003) Influence of Stress Magnitude on Water Loss and Chondrocyte Viability in Impacted Articular Cartilage. Journal of Biomechanical Engineering, 125:594-601.
Lucchinetti, E., Bhargava, M.M. and Torzilli, P.A. (2004) The Effect of Mechanical Load on the Expression of the Integrin Subunits α5 and β1 in Chondrocytes from Mature and Immature Cartilage Explants. Cell and Tissue Research, 315:385-391.
Milentijevic, D. and Torzilli, P.A. (2005) Influence of Stress Rate on Water Loss, Matrix Deformation and Chondrocyte Viability in Impacted Articular Cartilage. Journal of Biomechanics, 38:493-502.
Levin, A.S., Chen, C-T. and Torzilli, P.A. (2005) Effect of Tissue Maturity on Cell Viability in Mechanically Loaded Articular Cartilage. Osteoarthritis and Cartilage, 13:488-496.
Torzilli, P.A., Deng, X-H. and Ramcharan, M. (2006) Effect of Compressive Strain on Cell Viability in Statically Loaded Articular Cartilage. Biomechanics and Modeling in Mechanobiology, 5:123-132.
Maher, S. A., Doty, S. B., Torzilli, P. A., Thornton, S., Lowman, A. M., Thomas, J. D., Warren, R., Wright, T. M., and Myers, E. (2007) Nondegradable hydrogels for the treatment of focal cartilage defects. J Biomedical Materials Research A, 83:145-155.
Wyatt, K. E-K., Bourne, J.W. and Torzilli, P.A. (2009) Deformation-Dependent Enzyme Mechanokinetic Cleavage of Type I Collagen. Journal of Biomechanical Engineering, 131: 051004-1-9.
For more publications, please see the PubMed listing.
Major areas of research are in the study of cell and tissue biology, function and biomechanics of articular cartilage in health and disease; the enzyme mechanokinetics of collagen catalysis; the engineering of biocompatible materials for repair and replacement of damaged tissues; and the design of novel approaches at the molecular level to enhance soft tissue repair and function. Basic and applied research is performed at the molecular, cellular, tissue and whole joint levels. Of particular interest are questions concerning how cells respond to injury or disease (metabolism); how cellular response effects the matrix components (composition and arrangement); how these changes influence the tissue's physical performance (biomechanical properties); how we can repair and restructure the tissue's damaged microstructure (termed tissue engineering) through normal biological pathways (cellular engineering) or synthetic pathways (molecular engineering); how natural and synthetic materials can be combined to produce biocompatible tissue constructs (biomaterials); how genetically engineered cells (gene therapy) can be used to repair damaged tissues; and how cells and biologically compatible biomaterials can be combined to produce a viable replacement for damaged tissues.
One of the goals of Hospital for Special Surgery (HSS) is to advance the science of orthopedic surgery, rheumatology, and related disciplines for the benefit of patients. Research staff at HSS may collaborate with outside companies for education, research and medical advances. HSS supports this collaboration in order to foster medical breakthroughs; however, HSS also believes that these collaborations must be disclosed.
As part of the disclosure process, this website lists Research staff collaborations with outside companies if the Research staff member received any payment during the prior year or expects to receive any payment in the next year. The disclosures are based on information provided by the Research staff and other sources and are updated regularly. Current ownership interests and leadership positions are also listed. Further information may be available on individual company websites.
Below are the healthcare industry relationships reported by Dr. Torzilli as of June 22, 2015.
By disclosing the collaborations of HSS Research staff with industry on this website, HSS and its Research staff make this information available to patients and the public, thus creating a transparent environment for those who are interested in this information. Further, HSS’ Conflicts of Interest Policy does not permit payment of royalties on products developed by him/her that are used on patients at HSS.
Feel free to ask the Research staff member about their relationship(s).