Xiang-Hua Deng, MD

Selected Publications

Deng, XH, Wu, ZY. “Clinical application of silicone rod in hand surgery”. ACTA of Chongqing medicine, (4):30, 1980.

Deng, XH, Tan, FS, Wu, ZY: “On surgical treatment of patients aged 12 years with muscular torticollis”, Chinese Journal of Surgery, (11): 690,1984.

Cooper, DE; Deng, XH-H; Burstein, AL; Warren, RF.: The Strength of the Central Third Patellar Tendon Graft: A Biomechanical Study. Am. J. Sports Med. 21 (6): 818-824, 1993.

Warner, J.P, Deng, X.H., Warren, R.F. and Torzilli, P.A. "Static Capsuloligamentous Restraints to Superior-Inferior Translation of the Glenohumeral Joint." American Journal of Sports Medicine, 20:675-685. 1993.

Maynard MJ. Deng XH, Warren R., Wickiewicz TL. The popliteofibular ligament. Rediscovery of a key element in posterolateral stability. Maynard MJ. Deng X. Wickiewicz TL. American Journal of Sports Medicine. 24(3): 311-6, 1996.

Moorman CT 3rd, Hussain SS, Warren RF, Deng XH, Wickiewicz TL, Torzilli PA. Anatomy of the coracoacromial veil. J Surg Orthop Adv. 17(2):69-73. 2008 summer.

Rodeo SA, Suzuki K, Deng XH, et al. Use of recombinant human bone morphogenetic protein-2 to enhance tendon healing in a bone tunnel American Journal of Sports Medicine 27: (4) 476-488 JUL-AUG 1999.

Ma CB, Kawamura S, Deng XH, Ying L, Schneidkraut J, Hays P, Rodeo SA. Bone morphogenetic proteins-signaling plays a role in tendon-to-bone healing: a study of rhBMP-2 and noggin. Am J Sports Med. 35(4):597-604 Apr; 2007.

Carson EW, Deng XH, Allen A, Wickiewicz T, Warren RF. “Evaluation of in situ graft forces of a 2-bundle tibial inlay posterior Cruciate ligament reconstruction at various flexion angles”. Arthroscopy, 23(5):488-95. 2007.

Hays PL, Kawamura S, Deng XH, Dagher E, Mithoefer K, Ying L, Rodeo SA. “The role of macrophages in early healing of a tendon graft in a bone tunnel”. J Bone Joint Surg Am. 90(3):565-79, 2008.

Bedi A, Fox AJ, Harris PE, Deng XH, Ying L, Warren RF, Rodeo SA. “Diabetes mellitus impairs tendon-bone healing after rotator cuff repair’. J Shoulder Elbow Surg. 19(7):978-88. 2010.

Hettrich CM, Gasinu S, Beamer BS, Fox A, Ying O, Deng XH, Rodeo SA. ”The effect of immobilization on the native and repaired tendon-to-bone interface”. J Bone Joint Surg Am. 15; 95(10):925-30, 2013.

For more publications, please see the PubMed listing.

Research Description

Dr. Deng joined HSS as a post-doctoral fellow of Drs. Insall and Burstein in orthopedics and biomechanics in 1987. Since 1989, Dr. Deng has collaborated extensively with Dr. Warren in the field of sports medicine research. He is currently a scientist in the Soft Tissue Research Laboratory in the Tissue Engineering, Regeneration and Repair Program. Before coming to HSS, Dr. Deng was an attending orthopedic surgeon at Chonqing Medical University, China.

Dr. Deng’s early research was focused on the biomechanical evaluation of total knee joint design, and biomechanics of shoulder and knee joints. He has been working on sports medicine injury and soft tissue repairs for over 30 years. He is a pioneer in designing and improving in vivo small animal research models of rat and mouse ACL reconstruction, tendinopathy and rotator cuff repair, etc. In addition, he has designed several mechanical devices that can be used in vivo to apply programmed cyclic mechanical loads to soft tissue (such as tendon and ligament) under healing, which allows us to evaluate the effect of mechanical load on soft tissue healing biology.

Since 2000, Dr. Deng has collaborated extensively with Drs. Rodeo and Warren in the area of sports medicine research. His current research is aimed at creating a collection of clinically-relevant animal surgery models as a foundation from which future research can be performed. His work involves characterization of the anatomy and biomechanics of native and post-surgical musculoskeletal structures of research animals that undergo surgical procedures analogous to those performed in orthopedic sports medicine, including ACL reconstruction, rotator cuff repair, subacromial decompression, etc. He additionally performed pivotal work in developing animal models for orthopedic pathologies including osteoarthritis and chronic tendinosis. The eventual goal of these studies is twofold: first, to further our understanding in the cellular and molecular mechanisms of tendon-to-bone and cartilage healing, the effect of mechanical load on the healing process, and ultimately the cumulative implications for postoperative functional recovery following surgical repairs for common clinical problems; and second, to bring knowledge gained from these studies to application in the clinic.

Dr. Deng also serves as a mentor to surgical and post-doctoral fellows, residents, and students from all over the world in basic translational research. His collaborative research projects have won prestigious awards from multiple orthopedic and sports medicine societies.

 

Contact Information

Office Locations

Caspary Research Building
541 East 71st Street
New York, NY 10021

Tel: 212.606.1378

Mailing Address

Hospital for Special Surgery
535 East 70th Street
New York, New York 10021

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