Institutional Review Board, Hospital for Special Surgery
April 25, 2006
The safety of study participants is our top priority. The trial is approved and periodically reviewed by an Institutional Review Board (IRB), which includes doctors, administrators, ethicists, and members of the general public. The safety of clinical trials is reviewed by the U.S. Food and Drug Administration.
Before enrolling in a clinical trial, the investigator will explain the purpose of the trial, its expected benefits, any possible risks or side effects, and what your role will be. This is the time to ask questions! If you want to join the trial, you must sign the informed consent documents. You can leave a clinical trial at any time without penalty.
For further information, see Understanding Clinical Trials.
This cross-sectional pilot study will evaluate the ability of magnetic resonance angiography (MRA) and Power Doppler Ultrasound (PDU) to identify abnormal synovial vasculature in the hand and wrist of adults with less than six months of inflammatory arthritis symptoms. MRA and PDU synovial vascularity scores will be correlated with clinical and serologic markers and with validated x-ray and magnetic resonance imaging (MRI) scores of disease severity.
The study will enroll 30 patients between August 2005 and October 2006 for a single, four hour study visit.
Lisa Vasanth, MD (Co-investigator)
Lisa A. Mandl, MD, MPH (Principal Investigator)