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HSS Research Institute

Effects of Dexmedetomidine on Motor and Somatosensory Evoked Potentials during Spine Surgery

IRB Number: 14132
(inactive trial)

Institutional Review Board, Hospital for Special Surgery

April 24, 2015

The safety of study participants is our top priority. The trial is approved and periodically reviewed by an Institutional Review Board (IRB), which includes doctors, administrators, ethicists, and members of the general public. The safety of clinical trials is reviewed by the U.S. Food and Drug Administration.

Before enrolling in a clinical trial, the investigator will explain the purpose of the trial, its expected benefits, any possible risks or side effects, and what your role will be. This is the time to ask questions! If you want to join the trial, you must sign the informed consent documents. You can leave a clinical trial at any time without penalty.

For further information, see Understanding Clinical Trials.

Principal Investigator

Ronald G. Emerson, MD


Michael K. Urban, MD, PhD
Sean W. Donegan
David Pinter


Cross over study of 34 patients, comparing the effects of two different intravenous anesthetic protocol, with and without dexmedetomidine, on motor and somatosensory evoked potentials.

Inclusion/Exclusion Criteria

Inclusion criteria are patients between ages 18 to 70 years undergoing multilevel posterior spine fusions requiring SSEP and MEP monitoring

Exclusion criteria are contraindications to any of the anesthetic medications included in the protocols, history of bradycardia and non-English speaking patients.

Contact Information

Ronald G. Emerson, MD