Inflammatory Arthritis Center

Inflammatory Arthritis Center Research

Advances in the treatment of inflammatory arthritis have made a dramatic difference in the lives of people with this disease. However, there is still much to be done. In the Inflammatory Arthritis Center (IAC), our goal is to expand the understanding of how and why inflammatory arthritis develops and to improve patient care. Highlights of some of the ongoing research include:


Patients may voluntarily be included in the Rheumatoid Arthritis (RA) Cohort. By joining the RA Cohort, patients have the opportunity to learn about active or planned research studies they may be eligible for. Enrolled patients can request information about studies that are of interest to them, and will be updated on a regular basis about studies and education programs in the Inflammatory Arthritis Center. Physicians and researchers, in turn, use the anonymized information in the RA cohort to better describe their RA patient population, and to identify potential subjects appropriate for IAC research projects.

For additional information please contact Caroline at

CATCH-US: Consortium of Early Arthritis Cohorts USA

Vivian Bykerk MD, is the principle investigator of CATCH-US, an observational study of patients diagnosed with “early rheumatoid arthritis” or ERA. The goal of CATCH-US is to better understand predictors of treatment response in ERA patients. This multicenter study has been enrolling at HSS since December 2014 with 4 additional sites starting enrollment in late 2015 in Baltimore, Denver, Jacksonville and Los Angeles.

For additional information please contact Kayte at

Perioperative Flare in Total Joint Replacement

Susan Goodman MD, Medical Chief of the Combined Arthritis Program (CAP) is the principal investigator of this study of RA patients undergoing joint replacement (arthroplasty). Dr. Goodman and collaborators are looking at patients with RA undergoing either total hip or total knee replacement. Their goals are to determine the rate of post-operative “flare” or disease worsening, the relationship of flare to perioperative medication withdrawal, and the relationship between post-operative disease flare and arthroplasty outcomes.

For additional information please contact Annie at or Ryan at

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Early Arthritis Initiative

The HSS Early Arthritis Initiative connects patients quickly and efficiently with a rheumatologist who can evaluate their joint pain and get each patient started on an appropriate course of treatment.