Research

Visiting Scientist

Horng-Chaung Hsu, MD

Appointments:
Visiting Scientist, Hospital for Special Surgery
Professor & Chairman, Department of Orthopedic Surgery, China Medical University Hospital
Professor & Chief, Department of Orthopaedics, School of Medicine, China Medical University
President, Taiwan Shoulder & Elbow Society

Research Interests:
Dr. Hsu is a visiting scientist at Hospital for Special Surgery from Taiwan. He is an orthopedic surgeon at China Medical University Hospital and a Professor of Medicine at China Medical University. He has had more than 25 years of clinical experience in Orthopedics and has a special interest in the use of new technology to solve patient problems. His major clinical interests include total joint replacement and sports medicine. His early research was focused on joint biomechanics. He was a research fellow at the Mayo Clinic, where he studied under the direction of Dr. Kai-Nan An, in 1993-1994. His research is currently focused on soft tissue engineering, specifically tissue/ implant integration.

Selected Publications:
Chen YJ, wei YY, Chen HT, Fong YC, Hsu CJ, Tsai CH, Hsu HC, Liu SH, Tang CH: Osteopontin Increases Migration and MMP-9 Up-regulation via Alphabeta3 Integrin, FAK, ERK, and NF-kappaB-dependent Pathway in Human Chondrosarcoma Cells. J Cell Physiol 2009 Oct;221(1):98-108.

Huang CY, LeeCY, Chen MY, Yang WH, Chen TH, Chang CH, Hsu HC, Fong YC, Tang CH: Stromal Cell-derived Factor-1/CXCR4 Enhanced Motility of Human Osteosarcoma Cells Involves MEK1/2, ERK and NF-kappaB-dependent Pathway. J Cell Physiol 2009 Oct;221(1):204-12.

Chiu YC, Lin CY, Chen CP, Huang KC, Tong KM, Tzeng CY, Lee TS, Hsu HC, Tang CH: Peptidoglycan Enhances IL-6 Production in Human Synovial Fibroblast via TLR2 Receptor, Focal Adhesion Kinase, Akt, and AP-1-dependent Pathway. J Immunol. 2009 Aug 15;183(4):2785-92.

Chiu YC, Shieh DC, Tong KM, Chen CP, Huang KC, Chen PC, Fong YC, Hsu HC, Tang CH: Involvement of AdipoR Receptor in Adiponectin-induced Motility and Alpha 2 Beta1 Integrin Up-regulation in Human Chondrosarcoma Cells Carcinogenesis. 2009 Jun 23. (Epub ahead of print)

Tsai TY, Lu TW, Kuo MY, Hsu HC: Quantification of Three-dimentional Movement of Skin Markers Relative to Functional Activities Biomedical Engineering: Application, Basis and Communication. (BME) 2009, 21(3) 223-32.

Nien YH, Chen ZB, Liang JI, Yeh ML, Hsu HC, Su FC: Fabrication and Cell Affinity of Polyvinyl Alcohol Nanofibers via Electrospinning. J Medical & Biological   Engineering 2009, 29(2): 98-101.

Lin HC, Lai WH, Shih YF, Chang CM, Lo CY, Hsu HC: Physiological Anterior Laxity in Healthy Young Females: The Effect of Knee Hyperextension and Dominance. Knee Surg Sports Traumatol Arthrosc. (accepted, June 2009)

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