Research News: Discoveries Leading to Cures

HSS Becomes an NIH Network Partner for RA and Lupus

The National Institutes of Health has awarded grants to 11 research groups across the United States to establish the Accelerating Medicines Partnership in Rheumatoid Arthritis and Lupus (AMP RA/Lupus) Network. The AMP RA/Lupus Network will analyze the interplay among biological pathways, including at the single cell level, in tissues of patients with RA and lupus. The goal is to integrate data from multiple genome-wide analytic approaches to generate a comprehensive understanding of the mechanisms of tissue damage in RA and lupus. Learn more

The David Z. Rosensweig Genomics Research Center

Understanding the Human Playbook
With a $5.6 million grant from the Tow Foundation, HSS created The David Z. Rosensweig Genomics Research Center, under the direction of Associate Chief Scientific Officer Dr. Lionel Ivashkiv. The goals are to define the regulation of genes associated with autoimmune and inflammatory diseases, and to develop more effective therapies for rheumatoid arthritis and systemic lupus erythematosus. Learn more

Multidisciplinary Approach to Identify Biomarkers for Arthritis Prevention

Dr. Scott Rodeo is co-Principal Investigator of a grant from the Arthritis Foundation to validate the use of new MRI techniques and biomarkers to identify the early signs of Osteoarthritis (OA) in patients who have had ACL tears and other sports injuries. In collaboration with investigators at the University of California-San Francisco and the Mayo Clinic in Rochester Minnesota, Dr. Rodeo and HSS colleagues in radiology, orthopaedics and basic science are developing tools to predict a patient’s risk of developing OA and determining the most effective therapeutic interventions. Read More

Healthcare Research Institute

Using the Past to Improve the Future
The Hospital’s new Healthcare Research Institute (HRI), under the leadership of Dr. Stephen Lyman, is leveraging the enormous breadth of clinical information available at HSS- where more than 29,000 surgeries and 330,000 outpatient visits were conducted last year- to translate informed outcomes into better treatments for patients. Learn more

Saving Pregnancies in Women with Lupus

Dr. Jane Salmon leads a multi-center research initiative, the PROMISSE study, to identify predictors of poor pregnancy outcomes in women with systemic lupus erythematosus (SLE). The study is providing insights on the genes and cellular pathways that can affect pregnancy in lupus patients and, potentially, cause miscarriage and preeclampsia in healthy women. Learn More

Hospital Volume Affects Outcome for Early Revision after Total Hip Arthroplasty

Revision total hip arthroplasty (THA) is associated with increased cost, morbidity, and technical challenge compared to primary THA. Patient databases from 2 states (California and New York), analyzed to evaluate the influence of patient-, community-, and hospital-related characteristics on the risk of early revision THA, demonstrated that that early revision THA is more common in patients who undergo primary THA at low-volume hospitals. Learn More

Training the Next Generation of Leaders

Kellen Award Program Fosters Emerging Physician-Scientists

Essential to Hospital for Special Surgery’s leadership in breakthrough research are its physician-scientists, who balance clinical care with the rigorous pursuit of medical research. HSS has established the Anna-Maria and Stephen Kellen Physician-Scientist Career Development Award program to cultivate the next generation of physician/scientists, The Anna-Maria and Stephen Kellen Foundation has provided $4.3 of support. Learn More

NIH-Funded Institutional Research Training Grants

Funding from the National Institute of Arthritis and Musculoskeletal and Skin Diseases provides support for the HSS Rheumatology Research Training Program and the Musculoskeletal Research Training Program to mentor and guide the academic careers of pre- and post-doctoral fellows in basic research and clinical research disciplines.

Suzanne Maher, PhD

Marjolein van der Meulen, PhD

Dr. Suzanne Maher, Associate Scientist and Associate Director of the HSS Tissue Engineering, Regeneration and Repair Program, and Dr. Marjolein van der Meulen, Associate Scientist, HSS Musculoskeletal Integrity Program and Chair, Department of Biomedical Engineering at Cornell University, are principal investigators of the recently renewed Musculoskeletal Training Program currently in its 31st year of funding.

Mary Crow, MD

Dr. Mary Crow, Senior Scientist and Physician-in-Chief, is principal investigator of the Rheumatology Training Program, currently in its 29th year of funding.

Leadership Positions

Dr. Mathias Bostrom, senior clinician scientist, was named President of the Orthopaedic Research Society (ORS). The inauguration took place at the ORS annual meeting held in Las Vegas, NV.

Dr. Jo Hannafin, senior clinician scientist, became the first female President of the American Orthopedic Society for Sports Medicine. Learn More

Dr. Adele Boskey Receives ORS Distinguished Investigator Award

Adele Boskey, MDAccording to the ORS, the Distinguished Investigator Award honors an individual with a record of innovative work as evidenced by publications, presentations and sustained research support. The award recognizes a scientist who has also demonstrated outstanding mentorship of research trainees, service to the professional community and academic collegiality. Learn More

Dr. Carl Blobel and Dr. Lionel Ivashkiv elected members of the Association of American Physicians

Dr. Carl Blobel and Dr. Lionel Ivashkiv were elected to the AAP, a professional organization dedicated to "the advancement of scientific and practical medicine". Nominations are based on innovation, impact, and enduring contributions of the investigator’s research.

Research Excellence Attracts Funding

HSS currently receives more than $12 million annually in grants from the National Institutes of Health (NIH) to support basic and clinical research activities. In addition, research is supported by grants from the Arthritis Foundation, Orthopaedic Research and Education Foundation, Alliance for Lupus Research, Lupus Research Institute, Rheumatology Research Foundation, Leukemia and Lymphoma Society and others. Learn more