Lepromatous Leprosy Mimicking Systemic Lupus Erythematosus

HSS Journal Volume 10, Number 3 October 2014

Doruk Erkan, MD, MPH
Doruk Erkan, MD, MPH

Associate Attending Rheumatologist, Hospital for Special Surgery
Associate Physician-Scientist, Barbara Volcker Center for Women and Rheumatic Disease

Michael D. Lockshin, MD
Michael D. Lockshin, MD

Attending Rheumatologist, Hospital for Special Surgery
Professor of Medicine, Weill Cornell Medical College
Director, Barbara Volcker Center for Women and Rheumatic Disease

Asli Karadeniz, MD

Department of Internal Medicine, Pendik Training and Research Hospital, Marmara University School of Medicine, Mimar Sinan
Department of Rheumatology, Hospital for Special Surgery

Lindsay Lally, MD

Department of Rheumatology, Hospital for Special Surgery

Cynthia Magro, MD

Department of Pathology and Laboratory Medicine, Weill-Cornell NewYork Presbyterian Hospital

Roger Levy, MD

Department Rheumatology, Universidade do Estado do Rio de Janerio, Brazil

Case Presentation

A 29-year-old Brazilian woman was referred for management of systemic lupus erythematosus (SLE) with antiphospholipid antibodies (aPL). Her symptoms were 1 year of intermittent fever and diffuse, tender, erythematosus, and nodular rash that began during her first pregnancy. She was treated with short course of low-dose corticosteroids, with resolution; however, she suffered an embryonic loss at 7 weeks.  Six months prior to admission, she had recurrence of the nodular rash with new onset arthralgia; a skin biopsy showed panniculitis. Tests done at that time showed lupus anticoagulant (LA), anticardiolipin antibody (aCL) IgM > 150 U (normal 0–7 U), anti-β2 glycoprotein-I (aβ2GPI) IgM > 150 U (normal <10 U), and aβ2GPI IgA of 135 U/mL (normal <10 U), the other isotypes being negative.

This article appears in HSS Journal: Volume 10, Issue 3.
View the full HSS Journal article at springerlink.com.

About the HSS Journal

HSS Journal, an academic peer-reviewed journal published three times a year, February, July and October. The Journal accepts and publishes peer reviewed articles from around the world that contribute to the advancement of the knowledge of musculoskeletal diseases and disorders.

 

Back in the Game Patient Stories: