A 29-year-old Brazilian woman was referred for management of systemic lupus erythematosus (SLE) with antiphospholipid antibodies (aPL). Her symptoms were 1 year of intermittent fever and diffuse, tender, erythematosus, and nodular rash that began during her first pregnancy. She was treated with short course of low-dose corticosteroids, with resolution; however, she suffered an embryonic loss at 7 weeks. Six months prior to admission, she had recurrence of the nodular rash with new onset arthralgia; a skin biopsy showed panniculitis. Tests done at that time showed lupus anticoagulant (LA), anticardiolipin antibody (aCL) IgM > 150 U (normal 0–7 U), anti-β2 glycoprotein-I (aβ2GPI) IgM > 150 U (normal <10 U), and aβ2GPI IgA of 135 U/mL (normal <10 U), the other isotypes being negative.
HSS Journal, an academic peer-reviewed journal published three times a year, February, July and October. The Journal accepts and publishes peer reviewed articles from around the world that contribute to the advancement of the knowledge of musculoskeletal diseases and disorders.