The Effects of Aging on the Development of Osteoarthritis

Richard F. Loeser Jr, MD
Section of Molecular Medicine, Wake Forest University School of Medicine
Winston-Salem, North Carolina 


Osteoarthritis (OA) and aging are closely related; however, aging alone does not cause OA, but rather promotes the development of OA when other risk factors are present. Despite the strong association between aging and OA, we have an incomplete understanding of the basic mechanisms by which aging contributes to the development of OA. Aging at the systemic level as well as at the level of joint tissues and the cells that create and maintain them could play a role.

This article appears in HSS Journal: Volume 8, Number 1.
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About the HSS Journal

HSS Journal, an academic peer-reviewed journal published three times a year, February, July and October. The Journal accepts and publishes peer reviewed articles from around the world that contribute to the advancement of the knowledge of musculoskeletal diseases and disorders.


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