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Dynamics of an Intervertebral Disc Prosthesis in Human Cadaveric Spines

HSS Journal

Low-back pain is a common, disabling medical condition, and one of the major causes is disc degeneration. Total disc replacements (TDR) are intended to treat back pain by restoring disc height and re-establishing functional motion and stability at the index level. The objective of this study was to determine the effect on ROM and stiffness after implantation of the ProDisc®-L device in comparison to the intact state. Twelve L5-S1 lumbar spine segments were tested in flexion/extension, lateral bending, and axial rotation with axial compressive loads of 600N and 1200N. Specimens were tested in the intact state and after implantation with the ProDisc®-L device. ROM was not significantly different in the implanted spines when compared to their intact state in flexion/extension and axial rotation, but increased in lateral bending. Increased compressive load did not affect ROM in flexion/extension or axial rotation, but did result in decreased ROM in lateral bending and increased stiffness in both intact and implanted spine segments. The ProDisc®-L successfully restored or maintained normal spine segment motion.

This article appears in HSS Journal: Volume 3, Number 2.
View the full article at springerlink.com.

About the HSS Journal
HSS Journal, an academic peer-reviewed journal, is published twice a year, February and September, and features articles by internal faculty and HSS alumni that present current research and clinical work in the field of musculoskeletal medicine performed at HSS, including research articles, surgical procedures, and case reports.


Headshot of Frank P. Cammisa Jr., MD
Frank P. Cammisa Jr., MD
Attending Orthopedic Surgeon, Hospital for Special Surgery
Professor of Surgery (Orthopaedics), Weill Cornell Medical College
Headshot of Federico P. Girardi, MD
Federico P. Girardi, MD

Attending Orthopaedic Surgeon, Hospital for Special Surgery
Professor of Orthopaedic Surgery, Weill Cornell Medical College
Associate Scientist, Research Division, Hospital for Special Surgery

Headshot of Timothy Wright, PhD
Timothy Wright, PhD
Senior Scientist, Hospital for Special Surgery
F.M. Kirby Chair, Orthopaedic Biomechanics

Kathleen N Meyers, MS
Department of Biomedical Mechanics and Materials

Deirdre A Campbell, M Eng
Department of Biomedical Mechanics and Materials

Joseph D Lipman, MS
Department of Biomedical Mechanics and Materials

Kai Zhang, MD
Spine Surgery, Spine Service, Hospital for Special Surgery

Elizabeth R Myers, PhD
Department of Biomedical Mechanics and Materials


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