Dr. Goldstein is board certified in both Neurology and Psychiatry, and holds subspecialty certification in Behavioral Neurology and Neuropsychiatry. His medical specialty is Cognitive Neurology and Neuropsychiatry, and he currently serves as Director of the Center for Cognitive Health in the Marcia Dunn and Jonathan Sobel Department of Neurology at HSS.
A graduate of the College of Arts and Sciences of Cornell University, Dr. Goldstein earned his medical degree from the State University of New York School of Medicine (Stony Brook). He completed his internship in Internal Medicine, and residency training in both Neurology and Psychiatry, at The New York Hospital–Cornell Medical Center. He was the Ronald Coles Fellow in Neuropsychiatry at Harvard Medical School, and completed NIH-funded post-doctoral training in brain imaging in the Functional Neuroimaging Laboratory of Weill Cornell Medical College.
From 2005 through 2018, Dr. Goldstein was founding director of the Center for Cognitive Health at the Mount Sinai School of Medicine. Identified as a strategic initiative by the medical school, the multidisciplinary program combined neurologists, neuropsychiatrists, neuropsychologists, and neuroradiologists, bridging across multiple brain-focused departments. The Center's novel architecture thereby comprised an innovative central portal for cognitive patient care, training, and research. Dr. Goldstein's program was one of the earliest in New York City to focus on the neuropsychiatry of neuromodulation, including pre-operative evaluation and post-operative management of deep brain stimulation (DBS). His program was the first in New York State to perform an amyloid PET scan for clinical assessment of possible Alzheimer's Disease, and was selected as a traumatic brain injury care center by the National Football League.
Formerly an Associate Professor at the Icahn School of Medicine at Mount Sinai, and Attending Neurologist at The Mount Sinai Hospital, he served as Director of Medical Student Education in Neurology, and launched a newly-accredited Fellowship in Behavioral Neurology and Neuropsychiatry. He is the recipient of numerous teaching awards, and has been recognized for teaching excellence by the American Academy of Neurology. Dr. Goldstein's trainees have advanced to faculty appointments at premier academic medical centers.
Dr. Goldstein's research focus has been emotional modulation of cognitive control, including the application of functional magnetic resonance imaging (fMRI) to identify neural mechanisms of the interaction of affect and cognition. He has published multiple neuroscientific research articles and book chapters and has been recognized by New York Magazine Best Doctors issue since 2015.
Center for Cognitive Health, Department of Neurology
Comprehensive cognitive diagnostics (customized brain imaging, neuropsychology testing)
Transcranial magnetic stimulation (TMS)
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Director, Center for Cognitive Health, Hospital for Special Surgery
Associate Attending Neurologist, Hospital for Special Surgery
American Academy of Neurology, Member
American Board of Psychiatry and Neurology (ABPN), Diplomate
American Neuropsychiatric Association, Member
American Psychiatric Association, Fellow
Cognitive Neuroscience Society, Member
United Council of Neurologic Subspecialties (UCNS), Diplomate
Behavioral Neurology and Neuropsychiatry, UCNS
New York Magazine Best Doctors, 2015-2021
State University of New York (Stony Brook)
New York Hospital - Cornell Medical Center, 1995
Neurology and Psychiatry, New York Hospital - Cornell Medical Center, 2000
Cognitive Neurology/Neuropsychiatry, Harvard Medical School, 2001
Brain Imaging, Weill Cornell Medical College, 2003
Goldstein MA, Olanow CW. Dementia in Parkinson's disease. In: Charney DS, Nestler E, Eds. Neurobiology of Mental Illness, 3rd Ed. Oxford University Press, 2009.
Harden CL, Goldstein M, Ettinger AB. Anxiety disorders in epilepsy. In Ettinger A, Kanner AM, eds. Psychiatric issues in epilepsy: a practical guide to diagnosis and treatment, 2nd ed. Philadephia: Lippincott Williams & Wilkins 2006.
Goldstein M, Silverman ME. The Neuropsychiatric Examination. In: Riggio S, ed. Psychiatric Clin North America 2005 28(3):507-47.
Goldstein M, Price B. Magnetic Resonance Imaging. In: Dougherty DD, Rauch SL, Rosenbaum JR, eds. Essentials of Neuroimaging for the Practitioner. Washington DC: American Psychiatric Publishing 2004.
Goldstein M, Price B. Non-Alzheimer dementias. In: Samuels M, ed. Office Practice of Neurology, 2nd Ed. Elsevier, 2003.
Price B, Goldstein M. Differential diagnosis of dementia. In: Samuels M, ed. Office Practice of Neurology, 2nd Ed. Elsevier, 2003.
Woehr J, Goldstein M. Geriatric dysthymia and other non-major depressive syndromes. In: Ellison J, ed. Geriatric Psychiatry. New York: Dekker, Inc. 2003.
Goldstein M, Woehr J, Price B. Neuropsychology of cognitive disorders. In: D'Haenen HAH, den Boer JA, Willner P, eds. Biological Psychiatry. West Sussex UK: John Wiley, 2002.
Goldstein M, Harden CL. Infectious disease. In: Ettinger AB, Devinsky O, eds. Managing Epilepsy and Co-existing Diseases. Boston: Butterworth Heinemann, 2002.
Goldstein M, DeAngelis L. Nervous system neoplasms. In: Hainline B, Devinsky O, eds. Advances in Neurology, Vol 90. Philadelphia: Lippincott Williams and Wilkins, 2002.
Silverman ME, Goldstein MA, Smith L, Reichenberg A, Lichtenstein P, Sandin S. History of depression with psychotic features modifies a woman's risk for depression after childbirth. Psychosis. 2020; 12(3):281-4.
Kaku M, Shin S, Goldstein M, Pleet, J, Fabian M. Neuromyelitis optica spectrum disorder in a patient with Kikuchi- Fujimoto disease. Neurology: Neuroimmunology & Neuroinflammation 2016;3(3).
Popeo DM, Goldstein MA. Design and piloting of an integrated neuroscience elective for medical students in clinical clerkships. Academic Psychiatry 2016;40:359-362.
Weisholtz DS, Root JC, Butler T, Tuscher O, Epstein J, Pan H, Protopopescu X, Goldstein M, Isenberg N, Brendel G, LeDoux J, Silbersweig D, Stern E. Beyond the amydala: linguistic threat modulates peri-sylvian semantic access cortices. Brain and Language 2015;151:12-22.
Mitsis EM, Riggio S, Kostakoglu L, Dickstein DL, Machac J, Delman B, Goldstein M, Jennings D, D'Antonio E, Martin J, Naidich TP, Aloysi A, Fernandez C, Seibyl J, DeKosky ST, Elder GA, Marek K, Gordon W, Hof PR, Sano M, Gandy S. NFL player and of a man with FTD and a severe head injury. Transl Psychiatry. 2014
Mitsis EM, Bender HA, Kostakoglu L, Machac J, Martin J, Woehr JL, Sewell MC, Aloysi A, Goldstein MA, Li C, Sano M, Gandy S. A consecutive case series with 18F florbetapir PET imaging in an urban dementia center: impact on quality of life, decision making, and disposition. Molecular Neurodegeneration 2014;9:10.
Silverman ME, Loudon H, Liu X, Mauro C, Leiter G, Goldstein MA. The neural processing of negative emotion postpartum: a preliminary study of amygdala function in postpartum depression. Archives of Women's Mental Health 2011;14(4):355-9.
Goldstein MA, Ivanov I, Silverman ME. Posterior cortical atrophy: an exemplar for renovating diagnostic formulation in neuropsychiatry. Comprehensive Psychiatry 2011;52(3):326-333.
Goldstone AB, Bronster DJ, Anyanwu AC, Goldstein MA, Filsoufi F, Adams DH, Chikwe J. Predictors and outcomes of seizures after cardiac surgery: a multivariate analysis of 2578 patients. Ann Thorac Surg 2011; 91(2):519.
Tuescher O, Protopopescu X, Pan H, Cloitre M, Butler T, Goldstein M, Root JC, Engelien A, Furman D, Silverman M, Yang Y, Gorman J, Ledoux J, Silbersweig D, Stern E. Differential activity of sub-genual cingulate and brainstem in panic disorder and PTSD. J Anxiety Disord 2011;25(2):251-7.
For more publications, please see the PubMed listing.
Cognitive Neuroscience Society 2020. Adams K, Ruth J, Goldstein M. Proposal for a working model for bi-directional neural-aesthetic translational application of neuroaesthetics.
Cognitive Neuroscience Society 2019. Goldstein M, Adams K, Ruth, J. Neuroaesthetics: the emerging neuroscience of the nexus of art and philosophy, with implications for the economics of the visual arts.
American Neuropsychiatric Association 2018. Goldstein M, Silverman M, Lida M, Aloysi A. Neural segregation of anticipatory anxiety, aversive stimulus fear, and healthy habituation.
Cognitive Neuroscience Society 2014. Goldstein M, Silverman M, Bind R, Aloysi A, Bender H. Neural mechanisms of emotional-cognitive dyscontrol in ALS.
Cognitive Neuroscience Society 2013. Bender HA, Goldstein M, Towns S, Krajniak M, Mlodnicka A, Marcuse L, Fields M, Aloysi A, Schuetz S, Soleimani L, Gandy S, Miley-Akerstedt A. Older adults with epilepsy exhibit significantly greater executive dysfunction than their matched peers with cortically-based neurodegenerative disease.
American Academy of Neurology 2013. Bender HA, Mitsis E, Sano M, Martin J, Woehr J, Miley-Akerstedt A, Towns S, Kostakoglu L, Goldstein M, Machac J, Gandy S Neuropsychological testing identifies patients with pathologic levels of β-amyloid in the living brain as demonstrated by florbetapir F18 positron emission tomography
Human Amyloid Imaging 2013. Mitsis E, Bender H, Kostakoglu L, Machac J, Martin J, Woehr J, Goldstein M, Sano M, Gandy S Florbetapir F18 positron emission tomography identification of beta-amyloid in the living brain: A consecutive clinical case series
Bender HA, Mitsis E, Sano M. Martin J. Woehr JL, Miley-Åkerstedt A, Towns SJ, Kostakoglu L, Goldstein MA, Machac J, Gandy S. Neuropsychological testing identifies patients with pathologic levels of β-Amyloid in the living brain as demonstrated by florbetapir F18 positron emission tomography
Mitsis EM, Riggio S, D'Antonio E, Goldstein M, DeKosky ST, Naidich TP, Delman B, Machac J, Kostakoglu L, Elder G, Sano M, Gandy S, Gordon W. Florbetapir scanning excludes Alzheimer's disease in a retired NFL Player with delayed cognitive impairment
Cognitive Neuroscience Society 2010. Silverman M, Yoo J, Naidich T, Goldstein M. Visual and executive cortex potentiation in response to emotional image stimuli implicitly presented within a cognitive-motor control task.
Identifying neural mechanisms of emotional modulation of cognitive control across brain imaging (e.g., fMRI)
Neurophysiologic (e.g., functional near-infrared spectroscopy (fNIRS))
Cognitive assessment (e.g., neuropsychology) methodologies
One of the goals of HSS is to advance the science of orthopedic surgery, rheumatology, and related disciplines for the benefit of patients. Physicians at HSS may collaborate with outside companies for education, research and medical advances. HSS supports this collaboration in order to foster medical breakthroughs; however HSS also believes that these collaborations must be disclosed.
As part of the disclosure process, this website lists physician collaborations with outside companies. The disclosures are provided by information provided by the physician and other sources and are updated regularly. Further information may be available on individual company websites.
As of October 28, 2021, Dr. Goldstein reported no relationships with healthcare industry.
By disclosing the collaborations of HSS physicians with industry on this website, HSS and its physicians make this information available to their patients and the public, thus creating a transparent environment for those who are interested in this information. Further, the HSS Conflicts of Interest Policy does not permit physicians to collect royalties on products developed by him/her that are used on patients at HSS.