New York—June 20, 2013
Although as many as 25 percent of patients undergoing surgery suffer from sleep apnea, few hospitals have policies to help manage the risks of this condition during surgery, and there is little evidence to help guide anesthesiologists and surgeons caring for these patients.
Sleep apnea, a disorder in which a person frequently stops breathing for short periods during sleep, not only makes for a restless night but also puts the person at increased risk of high blood pressure, diabetes, heart attack and stroke. But although the condition is more common than diabetes, and poses particular hazards during surgery, relatively little research has been done to help guide clinicians.
“Patients with sleep apnea may be at risk for many complications during surgery, including airway blockage and intubation problems,” said Dr. Memtsoudis. “But that’s not all: we know that apnea affects many other organ systems as well. The American Society of Anesthesiologists published guidelines in 2006 to help us take better care of patients with sleep apnea, but there was—and still is--very little research to support these recommendations.”
The current guidelines recommend a period of pre-operative evaluation for patients with sleep apnea; the use of continuous positive airway pressure (CPAP); the use of local or regional anesthesia or perioperative nerve blocks rather than general anesthesia; and extended periods of observation of the patient during the post-surgical period.
“But there is insufficient evidence to tell us whether these actions actually have any effect,” said Dr. Memtsoudis. “And as we continue to see an increase in the number of surgical patients with sleep apnea, it creates a significant financial burden for hospitals at a time when health care costs are skyrocketing.”
Perhaps as a result of the lack of evidence, less than one in four hospitals in the United States and Canada have policies in place for the management of surgical patients with sleep apnea.
“We are fortunate, at Hospital for Special Surgery, to have the expertise and logistics in place to provide the great majority of our patients with the option to receive regional anesthesia, perioperative CPAP and monitoring if necessary and deemed appropriate. But we are mindful that these approaches require extensive resources that may be hard to justify given the high cost and lack of evidence that they truly change outcomes.”
Regional anesthesia, for example, has direct costs that are similar to general anesthesia, but requires expertise and resources that are not available everywhere. In the rest of the country, three quarters of joint replacement procedures are performed under general anesthesia.
In May, Dr. Memtsoudis published the first study to date that provides evidence about specific techniques for the safe management of patients with sleep apnea surrounding surgery. That study found that the use of regional anesthesia, rather than general anesthesia, reduced major complications by 17 percent in patients with sleep apnea undergoing joint surgery.
“We need much more research like this,” he said.
Working with key members of the new Society for Anesthesia and Sleep Medicine, Dr. Memtsoudis and his colleagues from the Department of Public Health at Cornell University are now designing a multicenter “practice based evidence” study that will collect data from institutions that have varying practices with regard to the management of sleep apnea in surgical patients. “This will help us assess what works and what doesn’t work and who among sleep apnea patients is actually at risk,” he said. “We can’t just advocate that people keep doing what they’re doing with no evidence for it.”
The editorial appears in the June 20, 2013, edition of the New England Journal of Medicine. Dr. Memtsoudis’ co-authors include Melanie C. Besculides, Dr.P.H., and Madhu Mazumdar, Ph.D., from NewYork-Presbyterian Hospital, Weill Cornell Medical College, New York City.
About HSS | Hospital for Special Surgery
HSS is the world’s leading academic medical center focused on musculoskeletal health. At its core is Hospital for Special Surgery, nationally ranked No. 1 in orthopedics (for the ninth consecutive year) and No. 3 in rheumatology by U.S.News & World Report (2018-2019). Founded in 1863, the Hospital has one of the lowest infection rates in the country and was the first in New York State to receive Magnet Recognition for Excellence in Nursing Service from the American Nurses Credentialing Center four consecutive times. The global standard total knee replacement was developed at HSS in 1969. An affiliate of Weill Cornell Medical College, HSS has a main campus in New York City and facilities in New Jersey, Connecticut and in the Long Island and Westchester County regions of New York State. In 2017 HSS provided care to 135,000 patients and performed more than 32,000 surgical procedures. People from all 50 U.S. states and 80 countries travelled to receive care at HSS. In addition to patient care, HSS leads the field in research, innovation and education. The HSS Research Institute comprises 20 laboratories and 300 staff members focused on leading the advancement of musculoskeletal health through prevention of degeneration, tissue repair and tissue regeneration. The HSS Global Innovation Institute was formed in 2016 to realize the potential of new drugs, therapeutics and devices. The culture of innovation is accelerating at HSS as 130 new idea submissions were made to the Global Innovation Institute in 2017 (almost 3x the submissions in 2015). The HSS Education Institute is the world’s leading provider of education on the topic on musculoskeletal health, with its online learning platform offering more than 600 courses to more than 21,000 medical professional members worldwide. Through HSS Global Ventures, the institution is collaborating with medical centers and other organizations to advance the quality and value of musculoskeletal care and to make world-class HSS care more widely accessible nationally and internationally.