Crippling disease that strikes mostly men

ABC 7—April 24, 2009

There are many types of arthritis, but there's one in particular that affects men, and it can be quite crippling. It's called ankylosing spondylitis and it devastates the spine.

And the disease goes back to ancient times. The 13th century B.C. Egyptian pharaoh Ramses showed evidence of having it, and as with all young patients, the disease must have altered his life.

And today, it still alters many men's lives.

Fifty-eight-year-old Michael Smith developed ankylosing spondylitis, or A.S., in 1980 and it changed his life.

The disease fused the 24 separate bones of his spine into a single poker stiff rod, and affected joints in his legs, as well.

"I was having some low back pain and went to see someone about it and he said I should take hot showers and that it was in my head," Michael said.

But Dr. Millicent Stone would not have given Michael that advice. She's a researcher at Hospital for Special Surgery working on A.S. and is aware of how early symptoms like his can later turn a spine and neck rigid.

"It can be devastating to patients and it affects them at a young age and it doesn't go away," Dr. Stone said.

The disease is hereditary and often begins in a person's teens and is much more common in men than in women.

But now, there is a breakthrough treatment that has come from research labs like the one at Hospital for Special Surgery.

Three drugs - enbrel, humira and remicade - can reduce the severe joint inflammation in the spine and other joints that causes the spinal bones to fuse. Remicade is used intravenously every two months or so. It can't reverse damage, but it may prevent the illness or limit its effects if given early in the disease.

Michael's using remicade. He now has more flexibility, even after just one treatment.

"It's overwhelming the fatigue that sits on you with spondylitis. It was just gone," said Michael.

To work best, the drugs should be started at the first sign of symptoms.

"We may have the opportunity to intervene in this window of opportunity and prevent this disease from progressing," Dr. Stone said.

Watch the full story at


Find a Physician

Conditions & Treatments

graphic: adult outline graphic: child outline
Select A Body Part
Conditions: Adult head Conditions: Adult spine Conditions: Adult shoulder Conditions: Adult elbow Conditions: Adult hand Conditions: Adult hip Conditions: Adult knee Conditions: Adult ankle Conditions: Adult head Conditions: Adult full body Conditions: Child spine Conditions: Child elbow Conditions: Child hip Conditions: Child hand Conditions: Child knee Conditions: Child ankle Conditions: Child full body

Complete Listing »

Media Contacts

Tracy Hickenbottom
Monique Irons
Sherry Randolph


Social Media Contacts

Andrew Worob
Otis Gamboa