HSS Physician Wins Award for Research on Common Antibiotic That Causes Ruptured Tendons

New York, NY—March 1, 1999

People taking a certain type of antibiotic to fight an infection may want to take it easy for more reasons than one. A common medication prescribed for strep throat, urinary tract infections and other ailments has been shown to cause ruptured tendons in patients who run, jump or lift weights while they are taking the drug and even for a few weeks after they stop, according to Riley Williams, MD, a sports medicine specialist at Hospital for Special Surgery.

Dr. Williams investigated why a class of antibiotics known as fluoroquinolones causes tendons to rupture in certain active or athletic patients. In the laboratory, Dr. Williams found that the antibiotic inhibits the cells that repair tendons and stimulates the production of enzymes that help to break them down. This weakens the tendon, leaving it susceptible to injury. "The fluoroquinolones are a valuable group of antibiotics to fight infection," Dr. Williams notes. "However, it would be prudent for anyone taking this type of antibiotic to avoid sports activities and strenuous exercise."

Dr. William’s research paper won the Best of Show Presentation at this year’s Annual Meeting of the American Academy of Orthopedic Surgeons and the O’Donoghue Award for Best Paper at the Annual Meeting of the American Orthopedic Society for Sports Medicine.

About Hospital for Special Surgery
Hospital for Special Surgery (HSS) is the world’s largest academic medical center focused on musculoskeletal health. HSS is nationally ranked No. 1 in orthopedics and No. 2 in rheumatology by U.S. News & World Report (2016-2017), and is the first hospital in New York State to receive Magnet Recognition for Excellence in Nursing Service from the American Nurses Credentialing Center four consecutive times. HSS has one of the lowest infection rates in the country. HSS is an affiliate of Weill Cornell Medical College and as such all Hospital for Special Surgery medical staff are faculty of Weill Cornell. The hospital's research division is internationally recognized as a leader in the investigation of musculoskeletal and autoimmune diseases. Hospital for Special Surgery is located in New York City and online at www.hss.edu.


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