Research at Hospital for Special Surgery is focused on identifying the mechanisms underlying musculoskeletal and autoimmune diseases, and developing effective approaches for prevention, diagnosis, and treatment. Interdisciplinary teams of clinicians and scientists collaborate to facilitate the translation of laboratory findings into clinical practice.

Our scientists are recognized worldwide for their expertise and collaborate in research studies around the globe. Mary Goldring, PhD, Senior Scientist in the Program on Tissue Engineering, Regeneration, and Repair, for example, is collaborating on a National Institutes of Health-funded project with the University of Southampton in the United Kingdom to determine the mechanisms of cartilage degradation in osteoarthritis.

Another researcher, Jane Salmon, MD, Senior Scientist in the Program on Autoimmunity and Inflammation, is collaborating on an NIH-funded study with Mt. Sinai Hospital in Toronto, Canada, among other sites, to determine the causes of pregnancy loss in women with systemic lupus erythematosus and other autoimmune diseases.

Clinical trials focused on conditions such as lupus, arthritis, joint replacement, osteoporosis, skeletal dysplasias, scleroderma, and other orthopedic and rheumatologic conditions are ongoing. These trials are conducted to determine the safety and efficacy of new drugs and devices in the search to better diagnose, prevent, and treat orthopedic and rheumatologic conditions. Eligible patients, domestic and international, may be asked to consider participating in clinical trials by their physicians. Participation in clinical trials is always voluntary.

In addition to working in the Arthroplasty Service, the Niarchos Fellow is given the opportunity to pursue clinical or basic science projects. The current Fellow is carrying out research in the Program on Arthritis and Tissue Degeneration on the causes of joint replacement loosening in arthritis patients. To learn more about the Niarchos Fellowship and other research training opportunities at HSS, please see our Academic Training Program.

Learn more about the Hospital for Special Surgery Research Division and HSS clinical trials.

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