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Severe Lupus with Nephritis and Catatonia; Excellent Response to Aggressive Treatment

This case appears in the HSS publication Grand Rounds from HSS - Management of Complex Cases, Fall 2014 - Volume 5, Issue 2, Case 1

Case 1, presented by Naveed Chaudhry, MD, Steven P. Salvatore, MD, and Kyriakos A. Kirou, MD describes a 34-year-old woman who was diagnosed with systemic lupus erythematosus (SLE) in 2011. Her serologic profile was positive for ANA, anti-dsDNA, anti-Sm and anti-RNP antibodies. After prior treatment elsewhere and significant medical events including a DVT, she first presented to HSS in February 2013 with marked leg edema and dyspnea on exertion. Past medical and family histories were unremarkable. Evaluation and renal biopsy revealed ISN/RPS Class V membranous lupus nephritis (Figures 1-3) with active disease in several organs. After aggressive multimodal treatment for her complex case involving multiple adjustments in management, the patient was able to go back to her job full-time.

Read full case details in Volume 5, Issue 2 of Grand Rounds - Complex Cases.

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