> Skip repeated content

Education Institute

Severe Lupus with Nephritis and Catatonia; Excellent Response to Aggressive Treatment

This case appears in the HSS publication Grand Rounds from HSS - Management of Complex Cases, Fall 2014 - Volume 5, Issue 2, Case 1

Case 1, presented by Naveed Chaudhry, MD, Steven P. Salvatore, MD, and Kyriakos A. Kirou, MD describes a 34-year-old woman who was diagnosed with systemic lupus erythematosus (SLE) in 2011. Her serologic profile was positive for ANA, anti-dsDNA, anti-Sm and anti-RNP antibodies. After prior treatment elsewhere and significant medical events including a DVT, she first presented to HSS in February 2013 with marked leg edema and dyspnea on exertion. Past medical and family histories were unremarkable. Evaluation and renal biopsy revealed ISN/RPS Class V membranous lupus nephritis (Figures 1-3) with active disease in several organs. After aggressive multimodal treatment for her complex case involving multiple adjustments in management, the patient was able to go back to her job full-time.

Read full case details in Volume 5, Issue 2 of Grand Rounds - Complex Cases.

Click on the image below to enlarge case figures and read the captions.

Download these images (.pdf)

Questions or Comments?

For any questions or comments regarding GRMCC, email complexcases@hss.edu.