Department of Biomechanics

Hongqiang Guo, PhD

Hongqiang Guo joined Hospital for Special Surgery in October 2012 as a Postdoctoral Fellow. His research focuses on the computational biomechanics of the soft tissues and the knee joint. His research project is funded by the National Institutes of Health (NIH). The aim of the NIH project is to define the relationship between the knee joint contact mechanics and the material and structural properties of native and substitute menisci during daily walking. This information is critical for the tissue engineer to design artificial menisci. He collaborates with research labs from Ohio State University and University of Rochester. He also works on multiscale modeling of the articular cartilage to understand the mechanical microenvironment (stress and strain) of the cell inside the articular cartilage. The aim of the project is to understand the initiation of the osteoarthritis (OA), a disease affecting millions of people around the world.

Dr. Guo has a background of both Biomedical Engineering and Mechanical Engineering. He gained his Bachelor of Engineering degree (2006) in Biomedical Engineering and Masters of Engineering (2008) in Mechanical Engineering from Xi'an Jiaotong University, China. He completed his doctoral studies in Biomedical Engineering at Rensselaer Polytechnic Institute in August 2012.


Leatherman, E. R., Guo, H., Gilbert, S., Hutchinson, I., Maher, S. A., and Santner, T. J., 2014. Using a statistically calibrated biphasic finite element model of the human knee joint to identify robust designs for a meniscal substitute, Journal of Biomechanical Engineering. In Press.

Guo, H., Maher, S. A., and Spilker, R. L., 2013. Biphasic finite element contact model of the knee joint using an augmented Lagrangian method. Medical Engineering and Physics, 35(9), 1313-1320.

Wazen, R. M., Currey, J. A., Guo, H., Brunski, J. B., Helms, J. A., and Nanci, A., 2013. Micromotion-induced strain fields influence early stages of repair at bone-implant interfaces. Acta Biomaterialia, 9(5), 6663-6674.

Guo, H., Shah, M., and Spilker, R. L., 2014. A finite element implementation for biphasic contact of hydrated porous media under finite deformation and sliding. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 228(3), 225-236.

Leucht, P., Monica, S. D., Temiyasathit, S., Lenton, K., Manu, A., Longaker, M. T., Jacobs, C. R., Spilker, R. L., Guo, H., Brunski, J. B., and Helms, J. A., 2013. Primary cilia act as mechanosensors during bone healing around an implant, Medical Engineering and Physics, 35(3), 392-402.