Jacques T. YaDeau, MD, PhD
Director, Clinical Research
Many intriguing aspects of anesthesia practice at HSS deserve study to improve orthopedic care and to showcase our clinical successes so others can emulate them. Knee and hip arthroplasty is a major area of interest, including pain management for up to two weeks after surgery. Research related to foot and ankle surgery has helped transform patient experience by efficiently prolonging peri-operative analgesia from nerve blockade. Investigations into the unique challenges of shoulder surgery address post-operative analgesia and seated-position physiology.
Dr. YaDeau’s research goals are:
Kathryn (Kate) DelPizzo, MD
Director, Pediatric Anesthesia & Pain Management
Dr. DelPizzo is one of two principal investigators at HSS for the Pediatric Regional Anesthesia Network (PRAN), a national database that tracks outcomes in children after regional and neuraxial anesthesia. This multi-institutional research tool allows pediatric anesthesiologists across the country to report and audit all their data on peripheral nerve blocks, spinals, and epidurals.
Dr. DelPizzo is the principal investigator for a study that will quantify the incidence of headache after spinal anesthesia in pediatric patients compared to adults. Her next project will embark on the study of post-operative narcotic use in adolescent surgical patients.
Stephen C. Haskins, MD
Assistant Attending Anesthesiologist
Dr. Haskins leads research initiatives focused on how to utilize point-of-care ultrasound (POCUS) in the peri-operative setting to improve patient assessment and outcomes. In the future, Dr. Haskins and the Research Division will evaluate the impact of a POCUS curriculum on anesthesiology resident and fellow training.
Kethy Jules-Elysees, MD
Associate Attending Anesthesiologist
Dr. Jules-Elysee's research evaluates the inflammatory stress response to surgery and its role in perioperative complications. Her research focuses on different modalities to reduce systemic inflammation and adverse postoperative events. In previous studies, she has shown that decreasing the stress response is associated with lower pain scores, improved rehabilitation milestones, and less lung injury.
Another research interest is to develop a multimodal pain regimen that will minimize and possibly eliminate the use of opioid analgesics.
Richard L. Kahn, MD
Medical Director, Ambulatory Surgery Center
Dr. Kahn is involved in studies focusing on anesthesia care for foot and ankle surgeries, spinal anesthetics for knee arthroscopies, and interscalene blocks for shoulder surgery to investigate the impact of regional anesthetic techniques on the patient's post-operative course.
Stavros Memtsoudis, MD, PhD
Senior Scientist & Professor of Anesthesiology
For over 15 years, Dr. Memtsoudis has conducted clinical- and population-based research in the field of peri-operative outcomes to investigate risk factors for complications and identify strategies to reduce them. His work on the influence of anesthesia-related factors on surgical outcomes has been recognized worldwide and has led to the creation of guidelines with the goal of improving the care of surgical patients.
Dr. Memtsoudis continues research on the topics of peri-operative sleep apnea, the influence of perioperative pain management strategies on outcomes, and the role of the anesthesiologist in preventing orthopedic surgery complications.
Nigel Sharrock, MB, ChemB
For the last 40 years, Dr. Sharrock has been an active clinician scientist, publishing over 100 peer-reviewed papers on anesthesia, its applications and effects on peri-operative outcomes following surgery. His research has involved introducing regional anesthesia for specific types of surgery, such as shoulder surgery, and developing new techniques such as mid-tarsal ankle block and studying the physiological effects of neuraxial anesthesia on orthopedic patients.
Dr. Sharrock studied the pharmacokinetics of local anesthetics to find maneuvers to make regional anesthesia safer and investigated the pathophysiology of the genesis of deep vein thrombosis (DVT) which has resulted in an approach called multimodal DVT prophylaxis, which incorporates regional anesthesia and focuses on ways to improve lower extremity blood flow rather than relying on potent anticoagulants. Dr. Sharrock’s research interests include the beneficial effects of regional anesthesia on outcomes following orthopedic surgery. Dr. Sharrock continues to study outcomes of hypotensive epidural anesthesia and its physiology.
Ellen Soffin, MD, PhD
Associate Director, Clinical Research
Dr. Soffin’s clinical research investigates ways of improving outcomes after orthopedic surgery. Her studies apply enhanced recovery after surgery (ERAS) concepts to spine surgery. She has developed the first ERAS pathway for major spine surgery. ERAS has been demonstrated in a range of surgical sub-specialties to reduce complications and length of stay, and improve patient satisfaction. Dr. Soffin is also conducting research into factors affecting same-day discharge after spine surgery, in particular, whether pain is a limiting factor.
Dr. Soffin also acts as a liaison between the Department of Anesthesiology and pharmaceutical companies interested in partnering with HSS for novel drug studies. A neuroscientist by training, Dr. Soffin was formerly responsible for developing new drugs for neurology and psychiatry indications at GlaxoSmithKline Pharmaceuticals. She now advises on the design of studies to evaluate new compounds and new indications for existing therapeutics for patients undergoing orthopedic surgery.
Michael K. Urban, MD, PhD
Director, Post-Anesthesia Care Unit
For the past several years, Dr. Urban has lead a team of anesthesiologists, neurologists and spine surgeons to conduct research with the goal of improved outcome after spine surgery, including:
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