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Lupus

Overview Text Audio Video
Pregnancy in Autoimmune and Musculoskeletal Disease View Profile Listen to Audio Presentation View Video Presentation
Mechanisms of Tissue Injury in Autoimmune Diseases such as Lupus; Autoimmune Disease and Atherosclerosis View Profile Listen to Audio Presentation View Video Presentation
Medical Management of Arthritis: Early Diagnosis and Current Therapies View Profile
Update on Smallpox and Flu Vaccinations View Profile
An In-Depth Topic Review of Systemic Lupus Erythematosus View Profile
Systemic Lupus Erythematosus - Board Review View Profile View Video Presentation
Ethical Issues in Rheumatology View Profile Listen to Audio Presentation View Video Presentation
Common Renal Problems in Rheumatology View Profile Listen to Audio Presentation View Video Presentation

Pathogenesis Text Audio Video
Do Viruses Cause Lupus? View Profile
Immunopathogenesis of Lupus and Other Autoimmune Diseases View Profile Listen to Audio Presentation View Video Presentation

Diagnosis Text Audio Video
Does ANA-negative lupus exist? What other labs are helpful when thinking of this diagnosis, and what if all of them are negative? View Profile

Therapy/Surgery Text Audio Video
Rituximab in the treatment of rheumatoid arthritis, systemic lupus, and other autoimmune diseases: past, present, and future View Profile
Lower the Thermostat - the Heat is Too High: Winning the Battle and the War View Profile
A Call to Arms: Treat Rheumatologic Disorders Early and Effectively with Disease-modifying Therapy View Profile
Our Amazing Progress - and More Within Rheumatology's Grasp View Profile
Mycophenolate Mofetil vs. IV Cyclophosphamide as Induction Therapy for Severe Lupus Nephritis View Profile
How long is it necessary to treat active SLE with immunosuppressive drugs? Can immunosuppressive therapy be discontinued? If so, when View Profile
Is there any difference in the prognosis of SLE patients who are diagnosed and treated early versus late in the disease? View Profile
How do patients respond to support groups such as those at HSS for lupus, rheumatoid arthritis, and myositis? Do patients with mild disease get upset seeing the severe cases? View Profile

Complications & Secondary Illness Text Audio Video
Common Pulmonary Problems in Rheumatology View Profile View Video Presentation
FDA Alert Regarding Lupus Medication: an HSS Rheumatology Perspective View Profile
Progressive Multifocal Leukoencephalopathy (PML) in Two Lupus Patients Treated with Rituximab (Rituxan): An HSS Rheumatology Perspective View Profile
Lupus vs. Preeclampsia View Profile
Lupus & Atherosclerosis: Should Recent Findings Alter Our Care of Lupus Patients? View Profile
In patients with lupus and osteoporosis, on prednisone, how would you deal with the osteoporosis when they become pregnant? Would your approach be different if they were not on steroids? View Profile
Steroid-Induced Osteoporosis View Profile Listen to Audio Presentation View Video Presentation
Lupus Nephritis: Are we progressing in our therapy? View Profile
How should proliferative glomerulonephritis with crescent formation be treated in young women with SLE? Will low-dose pulse cyclophosphamide (Cytoxan) and/or mycophenolate mofetil (CellCept) do the job while preserving fertility? View Profile
High-Risk Pregnancy in Lupus Patients View Profile Listen to Audio Presentation View Video Presentation

Research Text Audio Video
HSS Manual Ch. 5 - Immunogenetic Aspects Of Rheumatic Diseases View Profile
The Use of Disease Registries in the Assessment of Autoimmune Disorders and Cognitive Abnormalities in Patients with Systemic Lupus Erythematosus View Profile Listen to Audio Presentation View Video Presentation
The Establishment of B Cell Tolerance in Humans View Profile Listen to Audio Presentation View Video Presentation

Clinical Trials Text Audio Video
A Phase 1b Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation study with an open-label extension to evaluate the safety and tolerability of multiple IV doses of Medi-545, a fully Human Anti-interferon-alpha Monoclonal Antibody, View Profile
A Phase I, Randomized, Double-blind, Placebo-controlled, Escalating Single- and Multiple-dose Study of the Safety, Tolerability, and Pharmakokinetics of RhuMab IFN alpha in Adults with Systemic Lupus Erythematosus View Profile
The Systemic Lupus Erythematosus (SLE) Activity Gene Expression (SAGE) Study View Profile
A Phase 3, Multi-Center, Randomized, Double-Blind, Placebo-Controlled 76 Week Study to Evaluate the Efficacy and Safety of Belimumab (GHS1006, LymphoStat-B), A fully Human monoclonal Anti-BlyS Antibody, in Subjects with Systemic Lupus Erythematosus (SLE). View Profile
A Sequential Adaptive Phase II/III Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Abatacept Versus Placebo on a Background of Mycophenolate Mofetil and Glucocorticosteroids View Profile
EXPLORER: A randomized, double-blind, placebo controlled, multicenter, phase II/III study to evaluate the efficacy and safety of rituximab in subjects with moderate to severe systemic lupus erythematosus View Profile
Autoimmune Disease Registry and Repository View Profile
PROMISSE: Predictors of Pregnancy Outcome: Biomarkers in Anti-Phospholipid Antibody Syndrome (APS) and Systemic Lupus Erythematosus (SLE) View Profile
MINDFULL: A Randomized, Controlled Pilot Study of a Cognitive Rehabilitation Intervention Program in Systemic Lupus Erythematosus Patients View Profile
Pilot and Feasibility Study of Modafinil Treatment to Improve Cognitive Efficiency in SLE Patients View Profile
LUNAR: A phase III, randomized, double-blind, placebo-controlled, multi-center study to evaluate the efficacy and safety of rituximab in subjects with class III or IV lupus nephritis View Profile
Fc Receptor Function in Normals and Systemic Lupus Erythematosus (SLE) View Profile
A Phase I, Randomized, Double-Blind, Placebo Controlled, Dose-Escalation Study To Evaluate Safety And Tolerability Of A Single IV Dose Of MEDI-545, A Fully Human Monoclonal Antibody Directed Against Interferon Alpha Subtypes View Profile