Emma Jane MacDermott, MD, MRCPI

Dr. Emma Jane MacDermott specializes in Pediatric Rheumatology. She completed her medical degree at Trinity College Dublin in 1996, and continued her pediatric training in Ireland. She has been a member of the Royal College of Physicians of Ireland since 2001, with specialty training in Medicine of Childhood. Dr. MacDermott joined Hospital for Special Surgery in 2005 when she began a fellowship in Pediatric Rheumatology.

Her clinical practice is geared towards children with juvenile arthritis and systemic autoimmune diseases, including systemic lupus erythematosus, scleroderma, dermatomyositis and vasculitis of childhood. She combines her clinical practice with continued involvement in research, with particular interest in the role of Interferon and other biomarkers in systemic lupus erythematosus and systemic sclerosis.

Appointments

Assistant Attending Physician in Pediatrics, Hospital for Special Surgery
Assistant Professor of Pediatrics, Weill Cornell Medical College

Specialty

Pediatrics
Rheumatology

Subspecialty

Pediatrics
Rheumatology

Special Expertise

Childhood arthritis
Childhood systemic lupus erythematosus
Childhood scleroderma
Childhood dermatomyositis
Vasculitic diseases of childhood

Affiliations

Royal College of Physicians of Ireland - member
American College of Rheumatology - member
Irish Society for Rheumatology - member

Languages

French, German, Irish (staff members speak Spanish, Portuguese)

Education

University of Dublin, Trinity College, Dublin, Ireland - MD

Internship

The Adelaide and Meath Hospital incorporating the National Children's Hospital, Dublin, Ireland

Residency

The Adelaide and Meath Hospital incorporating the National Children's Hospital, Dublin, Ireland

Fellowship

Hospital for Special Surgery

Certification

Member of the Royal College of Physicians of Ireland, 2001

State Licensure

New York and Ireland  

Emma Jane MacDermott, MD, MRCPI has contributed to the following articles on HSS.edu:

Selected Publications

Papers:

MacDermott EJ, Adams A, Lehman TJ. Systemic lupus erythematosus in children: current and emerging therapies. Lupus, 2007; 16(8):677-83.

MacDermott EJ, Lehman TJ. Antiphospholipid syndrome in children: review of pathogenesis, diagnosis and treatment. Future Rheumatology, Apr 2007, Vol. 2, No. 2, pages 203-211.

MacDermott EJ, Lehman TJA. Clinical trials Report: the role of gene transcript signature in the diagnosis of Systemic Onset Juvenile Idiopathic arthritis. Current Rheumatology Reports, Volume 10, Issue 2: (in press).

MacDermott EJ, Lehman TJ. Prospective, open-label trial of rituximab in childhood systemic lupus erythematosus. Curr Rheumatol Rep., 2006 Dec; 8(6):439-41.Comment on: Arthritis Rheum. 2005 Oct; 52(10):3168-74.

Adams A, MacDermott EJ, Lehman TJ. Pharmacotherapy of lupus nephritis in children: a recommended treatment approach. Drugs. 2006; 66(9):1191-207.

MacDermott EJ, AJ Nicholson. Colic and Vaccination. Modern Medicine, April 2003, Vol 33, No. 4.

MacDermott EJ, AJ Nicholson. Immunisation Rate: Ireland vs. Europe. Forum, The Journal of the Irish College of General Practitioners, January 2003.

MacDermott EJ, AJ Nicholson. Actions needed to reach immunization Targets. Forum, The Journal of the Irish College of General Practitioners, September 2002.

Daly E, MacDermott EJ, Green A. Diagnostic review of 66 children with learning disability attending a single centre. Ir Med J. 2001 Jun; 94(6):184-5.

Abstracts:

Emma Jane MacDermott, Julie Cherian, Annie G. Santiago, Ziad Taimeh, Lilliana Barillas-Arias, Mary K. Crow, Kyriakos Kirou. Type 1 Interferon Pathway Activation Predicts Flares of Disease Activity in SLE. Arthritis and Rheumatism. Vol 58, no , December 2008 abst L6 pg:  (in press).

Emma Jane MacDermott, Lilliana Barillas-Arias, Ziad A. Taimeh, Annie G. Santiago, Mansi Mehta, Roland Duculan, Robert Spiera, Mary K. Crow, Kyriakos Kirou. Activation of the Type I IFN Pathway in Systemic Sclerosis (SSc) is detected at the level of PBMC Gene Expression: Association with Higher Skin Scores, Inflammatory Markers and anti-Ro Antibodies (ACR 2008 Poster 1139/400). Arthritis and Rheumatism. Vol 58, no 9, September 2008, abst 1139 page S592.

MacDermott EJ, Barillas-Arias L, Metha M, Duculan R, Santiago AG, Gordon E, Spiera R, Crow MK, Kirou KA. Activation of Type 1 interferon pathway in patients with systemic sclerosis (SSc) is associated with diffuse disease, antibodies to Ro and absence of Caucasian race. Arthritis and Rheumatism. Vol 56, no 12, December 2007, abst 548(F10) page 4244.

Barillas-Arias L, MacDermott EJ, Duculan R, Santiago AG, Gordon E, Cole P, Crow MK, Kirou KA. Longitudinal prospective study of type I interferon pathway activation as a biomarker of disease activity in patients with Systemic Lupus Erythematosus. Arthritis and Rheumatism. Vol56, no 12, Dec 2007, abst 550(F12) page 4245.

Adams A, Barillas L, Angeles ST, MacDermott EJ, Barinstein L, Lehman TJA. Cyclophosphamide and Rituximab Combination Therapy for the Treatment of Juvenile
Onset Scleroderma: 6 Patient Case Series. Arthritis and Rheumatism. 2006, 54 suppl: S169.

Barillas L, Adams A, Angeles ST, MacDermott EJ, Barinstein L, Lehman TJA. Combination Cyclophosphamide and Rituximab for the Treatment of Childhood Onset SLE. Arthritis and Rheumatism. 2006, 54 suppl: S689-90.

Moorthy LN, Peterson MG, Chalom E, Eulie B, Onel K, Baratelli M, Harrison M, Hashkes P, Bork D, Reiff A, Hong S, Adams A, Barinstein L, MacDermott EJ, Barillas L, Angeles ST, Belasco J, Mansour A, Haines K, Tabussi D, Vazquez L, Lehman TJA. Relationship of simple measure of impact of lupus erythematosus in youngsters (SMILEY) to change in disease activity and damage over time. Arthritis and Rheumatism. 2007, 56 suppl: s369.

Moorthy LN, Peterson MG, Baratelli M, Adams A, Barillas L, MacDermott EJ, Angeles S, Barinstein L, Onel K, Spencer C, Wagner-Weiner L, Levey E, Harrison M, Chalom E, Eulie B, Haines K, Tabussi D, Vasquez L, Lehman T. Simple Measure of Impact of Lupus Erythematosus in Youngsters (SMILEY)- Validity, Internal Consistency and Test retest Reliability. Arthritis and Rheumatism. 2006, 54 suppl: S162.

For more publications, please see the PubMed listing.

Selected Presentations

“Responsiveness of Simple Measure of Impact of Lupus in Youngsters© to Change in Disease Activity.” Moorthy LN, Peterson MG, Baratelli M, Harrison M, Onel K, Chalom E, Eulie B, Adams A, Barillas L, MacDermott EJ, Angeles S, Barinstein L, Hashkes P, Bork D, Reiff A, Hong S, Vazquez L, Lehman TJA.
European League against Rheumatism (EULAR), 2007.

“Simple Measure of Impact of Lupus in Youngsters©-Responsiveness to Change in SLE Activity.” Moorthy LN, Peterson MG, Baratelli M, Harrison M, Onel K, Chalom E, Eulie B, Adams A, Barillas L, MacDermott EJ, Angeles S, Barinstein L, Hashkes P, Bork D, Reiff A, Hong S, Vazquez L, Lehman TJA. Pediatric Rheumatology European Society (PRES), 2007.

“Simple Measure of Impact of Lupus Erythematosus In Youngster’s (SMILEY) - Responsiveness to Change in Disease Activity.” Moorthy LN, Peterson MG, Baratelli M, Harrison M, Onel K, Chalom E, Eulie B, Adams A, Barinstein L, MacDermott EJ, Barillas L, Angeles S, Hashkes P, Bork D, Reiff A, Hong S, Vazquez L, Lehman TJA.
Eastern Society for Pediatric Research (ESPR) Meeting, 2007.

“Multicenter validation of simple measure of impact of lupus erythematosus in youngsters - a new quality of life measure in pediatric lupus.” Moorthy LN, Peterson MG, Onel KB, Baratelli M, Haines K, Tabussi D, Chalom E, Eulie B, Harrison M, Adams A, MacDermott EJ, Barillas L, Angeles S, Barinstein L, Charette G, Vazquez L, Lehman TJA. American College of Rheumatology, 2005 and EULAR, 2006.

“Celiac Disease and Pediatric Rheumatic Diseases – A Case Series.” Moorthy LN, Adams A, Onel K, Peterson M, Vazquez L, MacDermott EJ, Barillas L, Baratelli M, Barinstein L, Lehman T. Poster Presentation. 3rd National Conference of Rheumatology Chapter, Indian Academy of Pediatrics. October, 2005.

 

Research Interests

Systemic Lupus Erythematosus (SLE)
Systemic Sclerosis
Role of Interferon Alpha and other biomarkers in auto immune disease