Research

Blood Metal Ions Level in Patients with Large Sized Ceramic or Metal Head Total Hip Arthroplasty

IRB Number: 13050

Institutional Review Board, Hospital for Special Surgery

June 26, 2013

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Principal Investigator

Chitranjan S. Ranawat, MD

Co-Investigators

Amar S. Ranawat, MD
Sarah West
Matin Lendhey

Summary

The research question is, is there a statistically significant difference between blood metal ions, emerging from head-trunnionjunction, in these two (large ceramic head and large metal head) groups?

Large ceramic heads: Study group

Large metal heads: Control group

We hypothesize that there is no difference between these groups. In other words, we expect no metal ions from the head-trunnion junction in either of these groups. Answering this question will shed light on large sized head type (either ceramic or metal) that is safe.

In this study, we will include 60 patients with 5 year follow-up


Inclusion/Exclusion Criteria

Inclusion Criteria:

a. Patients who received either large sized (32 or 36mm) ceramic head on highly cross-linked polyethylene (HXLPE) bearing (Cases) or received large sized (36mm) metal head on HXLPE bearing (Control) during THA.
b. Patients above 18 years old
c. All patients will be within the same post-op time frame (5 year post-op) and that ion levels will be tested 5 years post index surgery on all patients.

Exclusion Criteria:

  • Patients with revision THA

Contact Information

Chitranjan S. Ranawat, MD
RanawatC@hss.edu
646.797.8710



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